Literature DB >> 12075030

DMLE+: Bayesian linkage disequilibrium gene mapping.

Jeff P Reeve1, Bruce Rannala.   

Abstract

SUMMARY: The program DMLE+ allows Bayesian inference of the location of a gene carrying a mutation influencing a discrete trait (such as a disease) and/or other parameters of interest (such as mutation age) based on the observed linkage disequilibrium at multiple genetic markers. DMLE+ uses either individual marker genotypes, or haplotypes, integrates over uncertain population allele frequencies, and can incorporate prior information about gene location from an annotated human genome sequence. AVAILABILITY: DMLE+ is available in both Windows GUI and portable UNIX command line versions at http://dmle.org.

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Year:  2002        PMID： 12075030     DOI： 10.1093/bioinformatics/18.6.894

Source DB:  PubMed          Journal:  Bioinformatics        ISSN： 1367-4803            Impact factor:   6.937


  63 in total

1.  A founding locus within the RET proto-oncogene may account for a large proportion of apparently sporadic Hirschsprung disease and a subset of cases of sporadic medullary thyroid carcinoma.

Authors:  Salud Borrego; Fred A Wright; Raquel M Fernández; Nita Williams; Manuel López-Alonso; Ramana Davuluri; Guillermo Antiñolo; Charis Eng
Journal:  Am J Hum Genet       Date:  2002-12-09       Impact factor: 11.025

2.  Ancient founder mutation is responsible for Imerslund-Gräsbeck Syndrome among diverse ethnicities.

Authors:  Cameron M Beech; Sandya Liyanarachchi; Nidhi P Shah; Amy C Sturm; May F Sadiq; Albert de la Chapelle; Stephan M Tanner
Journal:  Orphanet J Rare Dis       Date:  2011-11-13       Impact factor: 4.123

3.  Detecting population growth, selection and inherited fertility from haplotypic data in humans.

Authors:  Frédéric Austerlitz; Luba Kalaydjieva; Evelyne Heyer
Journal:  Genetics       Date:  2003-11       Impact factor: 4.562

4.  An ancient autosomal haplotype bearing a rare achromatopsia-causing founder mutation is shared among Arab Muslims and Oriental Jews.

Authors:  Lina Zelinger; Alex Greenberg; Susanne Kohl; Eyal Banin; Dror Sharon
Journal:  Hum Genet       Date:  2010-06-13       Impact factor: 4.132

5.  Detecting genome wide haplotype sharing using SNP or microsatellite haplotype data.

Authors:  Melanie Bahlo; Jim Stankovich; Terence P Speed; Justin P Rubio; Rachel K Burfoot; Simon J Foote
Journal:  Hum Genet       Date:  2005-12-14       Impact factor: 4.132

6.  Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes.

Authors:  Etienne Patin; Luis B Barreiro; Pardis C Sabeti; Frédéric Austerlitz; Francesca Luca; Antti Sajantila; Doron M Behar; Ornella Semino; Anavaj Sakuntabhai; Nicole Guiso; Brigitte Gicquel; Ken McElreavey; Rosalind M Harding; Evelyne Heyer; Lluis Quintana-Murci
Journal:  Am J Hum Genet       Date:  2006-01-13       Impact factor: 11.025

7.  Age and founder effect of SOD1 A4V mutation causing ALS.

Authors:  M Saeed; Y Yang; H-X Deng; W-Y Hung; N Siddique; L Dellefave; C Gellera; P M Andersen; T Siddique
Journal:  Neurology       Date:  2009-01-28       Impact factor: 9.910

8.  Confirmation of the type 2 myotonic dystrophy (CCTG)n expansion mutation in patients with proximal myotonic myopathy/proximal myotonic dystrophy of different European origins: a single shared haplotype indicates an ancestral founder effect.

Authors:  Linda L Bachinski; Bjarne Udd; Giovanni Meola; Valeria Sansone; Guillaume Bassez; Bruno Eymard; Charles A Thornton; Richard T Moxley; Peter S Harper; Mark T Rogers; Karin Jurkat-Rott; Frank Lehmann-Horn; Thomas Wieser; Josep Gamez; Carmen Navarro; Armand Bottani; Andre Kohler; Mark D Shriver; Riitta Sallinen; Maija Wessman; Shanxiang Zhang; Fred A Wright; Ralf Krahe
Journal:  Am J Hum Genet       Date:  2003-09-10       Impact factor: 11.025

9.  A founder MLH1 mutation in Lynch syndrome families from Piedmont, Italy, is associated with an increased risk of pancreatic tumours and diverse immunohistochemical patterns.

Authors:  Iolanda Borelli; Guido C Casalis Cavalchini; Serena Del Peschio; Monica Micheletti; Tiziana Venesio; Ivana Sarotto; Anna Allavena; Luisa Delsedime; Marco A Barberis; Giorgia Mandrile; Paola Berchialla; Paola Ogliara; Cecilia Bracco; Barbara Pasini
Journal:  Fam Cancer       Date:  2014-09       Impact factor: 2.375

10.  Mutation history of the roma/gypsies.

Authors:  Bharti Morar; David Gresham; Dora Angelicheva; Ivailo Tournev; Rebecca Gooding; Velina Guergueltcheva; Carolin Schmidt; Angela Abicht; Hanns Lochmuller; Attila Tordai; Lajos Kalmar; Melinda Nagy; Veronika Karcagi; Marc Jeanpierre; Agnes Herczegfalvi; David Beeson; Viswanathan Venkataraman; Kim Warwick Carter; Jeff Reeve; Rosario de Pablo; Vaidutis Kucinskas; Luba Kalaydjieva
Journal:  Am J Hum Genet       Date:  2004-08-20       Impact factor: 11.025
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