Literature DB >> 12074714

Distribution of HLA-B alleles in nasopharyngeal carcinoma patients and normal controls in Thailand.

Nattiya Pimtanothai1, P Charoenwongse, A Mutirangura, C K Hurley.   

Abstract

HLA-B frequencies in 54 unrelated nasopharyngeal carcinoma (NPC) patients and 49 healthy random controls in Thailand were investigated by direct DNA sequencing. Similar to previous reports in Chinese NPC patients, HLA-B*4601 was observed at a greater frequency in patients (21/54 (40%)) compared to controls (7/49 (14%). An increase in HLA-B*51012 was also demonstrated. B*51012 was present in 6/54 (11%) NPC patients but was not observed (0%) in controls. B*44032 was associated with a decreased risk. Five out of 54 (9%) NPC patients had B*44032 compared to 14/49 (29%) in the control group.

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Year:  2002        PMID： 12074714     DOI： 10.1034/j.1399-0039.2002.590308.x

Source DB:  PubMed          Journal:  Tissue Antigens        ISSN： 0001-2815


  7 in total

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Journal:  J Pers Med       Date:  2021-05-07

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  7 in total

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