Literature DB >> 12074486

Viral agents as biological weapons and agents of bioterrorism.

Michael S Bronze1, Mark M Huycke, Linda J Machado, Gene W Voskuhl, Ronald A Greenfield.   

Abstract

Multiple viral agents have been classified by the CDC as potential weapons of mass destruction or agents for biologic terrorism. Agents such as smallpox, viral hemorrhagic fever viruses, agents of viral encephalitis, and others are of concern because they are highly infectious and relatively easy to produce. Although dispersion might be difficult, the risk is magnified by the fact that large populations are susceptible to these agents and only limited treatment and vaccination strategies exist. Although the risk of large-scale bioterrorism using viral agents is small, public health programs and health care providers must be prepared for this potentially devastating impact on public health.

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Year:  2002        PMID: 12074486     DOI: 10.1097/00000441-200206000-00004

Source DB:  PubMed          Journal:  Am J Med Sci        ISSN: 0002-9629            Impact factor:   2.378


  30 in total

Review 1.  Next-generation sequencing in clinical virology: Discovery of new viruses.

Authors:  Sibnarayan Datta; Raghvendra Budhauliya; Bidisha Das; Soumya Chatterjee; Vijay Veer
Journal:  World J Virol       Date:  2015-08-12

2.  Purification, crystallization and X-ray diffraction analysis of the C-terminal protease domain of Venezuelan equine encephalitis virus nsP2.

Authors:  Andrew T Russo; Stanley J Watowich
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2006-05-05

Review 3.  Treatment of hantavirus pulmonary syndrome.

Authors:  Colleen B Jonsson; Jay Hooper; Gregory Mertz
Journal:  Antiviral Res       Date:  2007-11-21       Impact factor: 5.970

4.  Venezuelan equine encephalitis virus variants lacking transcription inhibitory functions demonstrate highly attenuated phenotype.

Authors:  Svetlana Atasheva; Dal Young Kim; Elena I Frolova; Ilya Frolov
Journal:  J Virol       Date:  2014-10-15       Impact factor: 5.103

5.  Novel inhibitors of neurotropic alphavirus replication that improve host survival in a mouse model of acute viral encephalitis.

Authors:  Janice A Sindac; Bryan D Yestrepsky; Scott J Barraza; Kyle L Bolduc; Pennelope K Blakely; Richard F Keep; David N Irani; David J Miller; Scott D Larsen
Journal:  J Med Chem       Date:  2012-04-03       Impact factor: 7.446

Review 6.  The role of HTS in drug discovery at the University of Michigan.

Authors:  Martha J Larsen; Scott D Larsen; Andrew Fribley; Jolanta Grembecka; Kristoff Homan; Anna Mapp; Andrew Haak; Zaneta Nikolovska-Coleska; Jeanne A Stuckey; Duxin Sun; David H Sherman
Journal:  Comb Chem High Throughput Screen       Date:  2014-03       Impact factor: 1.339

7.  Treatment of mice with human monoclonal antibody 24h after lethal aerosol challenge with virulent Venezuelan equine encephalitis virus prevents disease but not infection.

Authors:  Ann R Hunt; Richard A Bowen; Shana Frederickson; Toshiaki Maruyama; John T Roehrig; Carol D Blair
Journal:  Virology       Date:  2011-04-13       Impact factor: 3.616

8.  Cracking the cell access code for the deadly virus VEEV.

Authors:  James Zengel; Jan E Carette
Journal:  Nature       Date:  2020-12       Impact factor: 49.962

9.  Mutations in Hypervariable Domain of Venezuelan Equine Encephalitis Virus nsP3 Protein Differentially Affect Viral Replication.

Authors:  Chetan D Meshram; Aaron T Phillips; Tetyana Lukash; Nikita Shiliaev; Elena I Frolova; Ilya Frolov
Journal:  J Virol       Date:  2020-01-17       Impact factor: 5.103

10.  Optimization of novel indole-2-carboxamide inhibitors of neurotropic alphavirus replication.

Authors:  Janice A Sindac; Scott J Barraza; Craig J Dobry; Jianming Xiang; Pennelope K Blakely; David N Irani; Richard F Keep; David J Miller; Scott D Larsen
Journal:  J Med Chem       Date:  2013-11-12       Impact factor: 7.446

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