BACKGROUND: The relation between gastro-esophageal reflux disease (GERD) and obesity is controversial. The laparoscopic adjustable gastric band (LAGB) procedure is effective for morbid obesity. Its indication in the presence of GERD, however, is still debated. This study aimed to investigate esophageal symptoms, motility patterns, and acid exposure in morbidly obese patients before and after LAGB placement. METHOD: For this study, 43 consecutive obese patients were investigated by a standardized symptoms questionnaire, stationary manometry and 24-h ambulatory pH-metry, and 16 patients with abnormal esophageal acid exposure were reevaluated 18 months after LAGB placement. RESULTS: Symptom scores and abnormal esophageal acid exposure were found to be significantly higher, Lower Esophageal Sphincter (LOS) pressure was significantly lower in obese patients than in control subjects. After LAGB, esophageal acid exposure was significantly reduced in all but two patients, who presented with proximal of gastric pouch dilation. CONCLUSIONS: There is a high prevalence of GERD in the obese population. Uncomplicated LAGB placement reduces the amount of acid in these patients with abnormal esophageal acid exposure.
BACKGROUND: The relation between gastro-esophageal reflux disease (GERD) and obesity is controversial. The laparoscopic adjustable gastric band (LAGB) procedure is effective for morbid obesity. Its indication in the presence of GERD, however, is still debated. This study aimed to investigate esophageal symptoms, motility patterns, and acid exposure in morbidly obesepatients before and after LAGB placement. METHOD: For this study, 43 consecutive obesepatients were investigated by a standardized symptoms questionnaire, stationary manometry and 24-h ambulatory pH-metry, and 16 patients with abnormal esophageal acid exposure were reevaluated 18 months after LAGB placement. RESULTS: Symptom scores and abnormal esophageal acid exposure were found to be significantly higher, Lower Esophageal Sphincter (LOS) pressure was significantly lower in obesepatients than in control subjects. After LAGB, esophageal acid exposure was significantly reduced in all but two patients, who presented with proximal of gastric pouch dilation. CONCLUSIONS: There is a high prevalence of GERD in the obese population. Uncomplicated LAGB placement reduces the amount of acid in these patients with abnormal esophageal acid exposure.
Authors: Martin Fried; Vojtech Hainer; Arnaud Basdevant; Henry Buchwald; Mervyn Deitel; Nicholas Finer; Jan Willem M Greve; Fritz Horber; Elisabeth Mathus-Vliegen; Nicola Scopinaro; Rudolf Steffen; Constantine Tsigos; Rudolf Weiner; Kurt Widhalm Journal: Obes Surg Date: 2007-02 Impact factor: 4.129
Authors: Robert W O'Rourke; Ann K Seltman; Eugene Y Chang; Kevin M Reavis; Brian S Diggs; John G Hunter; Blair A Jobe Journal: Ann Surg Date: 2006-11 Impact factor: 12.969
Authors: M A Küper; K M Kramer; A Kirschniak; A Kischniak; M Zdichavsky; J H Schneider; D Stüker; T Kratt; A Königsrainer; F A Granderath Journal: Obes Surg Date: 2009-06-10 Impact factor: 4.129
Authors: Paul Robert Burton; Wendy A Brown; Cheryl Laurie; Anna Korin; Kenneth Yap; Melissa Richards; John Owens; Gary Crosthwaite; Geoff Hebbard; Paul E O'Brien Journal: Obes Surg Date: 2009-09-18 Impact factor: 4.129