Literature DB >> 12072276

New technologies for studying immune regulation in ruminants.

Gary Entrican1.   

Abstract

There remains a great need for the development of reagents and techniques to study immune regulation in ruminants. These tools are fundamental to our understanding of the mechanisms of immune modulation and underpin the rational design of disease control strategies in livestock. Technological advances in molecular biology have resulted in the development of a new range of techniques to measure and quantify gene expression in normal and disease states. However, the ability to measure protein expression, produce proteins (usually in recombinant form) and to block receptor-ligand interactions remains essential for elucidating the function of the molecules of interest. The aims of this workshop were to look at the current status of reagents for studying ruminant immunology, the prospects for future developments, and also to discuss reagents availability between different groups worldwide.

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Year:  2002        PMID: 12072276     DOI: 10.1016/s0165-2427(02)00082-x

Source DB:  PubMed          Journal:  Vet Immunol Immunopathol        ISSN: 0165-2427            Impact factor:   2.046


  4 in total

1.  Design and evaluation of a unique SYBR Green real-time RT-PCR assay for quantification of five major cytokines in cattle, sheep and goats.

Authors:  Carinne Puech; Laurence Dedieu; Isabelle Chantal; Valérie Rodrigues
Journal:  BMC Vet Res       Date:  2015-03-17       Impact factor: 2.741

2.  Quantification and phenotypic characterisation of peripheral IFN-γ producing leucocytes in chickens vaccinated against Newcastle disease.

Authors:  S H Andersen; L Vervelde; K Sutton; L R Norup; E Wattrang; H R Juul-Madsen; T S Dalgaard
Journal:  Vet Immunol Immunopathol       Date:  2017-10-10       Impact factor: 2.046

3.  Enhancing the toolbox to study IL-17A in cattle and sheep.

Authors:  Sean R Wattegedera; Yolanda Corripio-Miyar; Yvonne Pang; David Frew; Tom N McNeilly; Javier Palarea-Albaladejo; Colin J McInnes; Jayne C Hope; Elizabeth J Glass; Gary Entrican
Journal:  Vet Res       Date:  2017-04-08       Impact factor: 3.683

4.  A Mini-Atlas of Gene Expression for the Domestic Goat (Capra hircus).

Authors:  Charity Muriuki; Stephen J Bush; Mazdak Salavati; Mary E B McCulloch; Zofia M Lisowski; Morris Agaba; Appolinaire Djikeng; David A Hume; Emily L Clark
Journal:  Front Genet       Date:  2019-11-04       Impact factor: 4.599

  4 in total

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