Literature DB >> 12069992

Neuroprotection and reduced proliferation of microglia in ribavirin-treated bornavirus-infected rats.

Marylou V Solbrig1, Robert Schlaberg, Thomas Briese, Nigel Horscroft, W Ian Lipkin.   

Abstract

In a rat model of Borna disease, intracerebral ribavirin caused clinical improvement without changes in virus titer or nucleic acid. Levels of microglia and infiltrating CD4 and CD8 cells were decreased, despite increases in mRNAs encoding interleukin-1beta (IL-1beta), IL-10, and gamma interferon in the brain. Intracerebral ribavirin may reduce morbidity through effects on microglia cell proliferation.

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Year:  2002        PMID： 12069992      PMCID： PMC127284          DOI： 10.1128/AAC.46.7.2287-2291.2002

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  44 in total

1.  Amantadine revisited: an open trial of amantadinesulfate treatment in chronically depressed patients with Borna disease virus infection.

Authors:  R Ferszt; K P Kühl; L Bode; E W Severus; B Winzer; A Berghöfer; G Beelitz; B Brodhun; B Müller-Oerlinghausen; H Ludwig
Journal:  Pharmacopsychiatry       Date:  1999-07       Impact factor: 5.788

2.  Inhibition of Borna disease virus replication by ribavirin.

Authors:  I Jordan; T Briese; D R Averett; W I Lipkin
Journal:  J Virol       Date:  1999-09       Impact factor: 5.103

3.  Ribavirin polarizes human T cell responses towards a Type 1 cytokine profile.

Authors:  R C Tam; B Pai; J Bard; C Lim; D R Averett; U T Phan; T Milovanovic
Journal:  J Hepatol       Date:  1999-03       Impact factor: 25.083

4.  Borna disease virus is not sensitive to amantadine.

Authors:  W Hallensleben; M Zocher; P Staeheli
Journal:  Arch Virol       Date:  1997       Impact factor: 2.574

5.  Ribavirin inhibits viral-induced macrophage production of TNF, IL-1, the procoagulant fgl2 prothrombinase and preserves Th1 cytokine production but inhibits Th2 cytokine response.

Authors:  Q Ning; D Brown; J Parodo; M Cattral; R Gorczynski; E Cole; L Fung; J W Ding; M F Liu; O Rotstein; M J Phillips; G Levy
Journal:  J Immunol       Date:  1998-04-01       Impact factor: 5.422

6.  Effect of immune priming on Borna disease.

Authors:  A J Lewis; J L Whitton; C G Hatalski; H Weissenböck; W I Lipkin
Journal:  J Virol       Date:  1999-03       Impact factor: 5.103

7.  Inhibition of Borna disease virus replication by ribavirin in persistently infected cells.

Authors:  T Mizutani; H Inagaki; K Araki; H Kariwa; J Arikawa; I Takashima
Journal:  Arch Virol       Date:  1998       Impact factor: 2.574

8.  Resistance of naive mice to murine hepatitis virus strain 3 requires development of a Th1, but not a Th2, response, whereas pre-existing antibody partially protects against primary infection.

Authors:  M F Liu; Q Ning; M Pope; T Mosmann; J Leibowitz; J W Ding; L S Fung; O Rotstein; R Gorczynski; G A Levy
Journal:  Adv Exp Med Biol       Date:  1998       Impact factor: 2.622

9.  The antiviral compound ribavirin modulates the T helper (Th) 1/Th2 subset balance in hepatitis B and C virus-specific immune responses.

Authors:  C Hultgren; D R Milich; O Weiland; M Sällberg
Journal:  J Gen Virol       Date:  1998-10       Impact factor: 3.891

10.  Borna disease in a dog with lethal meningoencephalitis.

Authors:  H Weissenböck; N Nowotny; P Caplazi; J Kolodziejek; F Ehrensperger
Journal:  J Clin Microbiol       Date:  1998-07       Impact factor: 5.948
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  7 in total

1.  Mechanism of the antiviral action of 1-beta-D-arabinofuranosylcytosine on Borna disease virus.

Authors:  Romain Volmer; Jeffrey J Bajramovic; Urs Schneider; Sandra Ufano; Sylvie Pochet; Daniel Gonzalez-Dunia
Journal:  J Virol       Date:  2005-04       Impact factor: 5.103

2.  A synthetic cannabinoid agonist promotes oligodendrogliogenesis during viral encephalitis in rats.

Authors:  Marylou V Solbrig; Yijun Fan; Neal Hermanowicz; Maria Grazia Morgese; Andrea Giuffrida
Journal:  Exp Neurol       Date:  2010-09-09       Impact factor: 5.330

Review 3.  Healthcare-associated exposure to Borna disease virus 1 (BoDV-1).

Authors:  Judith Reinmiedl; Heiko Schulz; Viktoria C Ruf; Moritz R Hernandez Petzsche; Jürgen Rissland; Dennis Tappe
Journal:  J Occup Med Toxicol       Date:  2022-06-09       Impact factor: 2.862

4.  Cannabinoid rescue of striatal progenitor cells in chronic Borna disease viral encephalitis in rats.

Authors:  Marylou V Solbrig; Neal Hermanowicz
Journal:  J Neurovirol       Date:  2008-05       Impact factor: 2.643

5.  2'-fluoro-2'-deoxycytidine inhibits Borna disease virus replication and spread.

Authors:  Jeffrey J Bajramovic; Romain Volmer; Sylvie Syan; Sylvie Pochet; Daniel Gonzalez-Dunia
Journal:  Antimicrob Agents Chemother       Date:  2004-04       Impact factor: 5.191

Review 6.  Avian Bornavirus Research-A Comprehensive Review.

Authors:  Dennis Rubbenstroth
Journal:  Viruses       Date:  2022-07-11       Impact factor: 5.818

7.  Occupation-Associated Fatal Limbic Encephalitis Caused by Variegated Squirrel Bornavirus 1, Germany, 2013.

Authors:  Dennis Tappe; Kore Schlottau; Daniel Cadar; Bernd Hoffmann; Lorenz Balke; Burkhard Bewig; Donata Hoffmann; Philip Eisermann; Helmut Fickenscher; Andi Krumbholz; Helmut Laufs; Monika Huhndorf; Maria Rosenthal; Walter Schulz-Schaeffer; Gabriele Ismer; Sven-Kevin Hotop; Mark Brönstrup; Anthonina Ott; Jonas Schmidt-Chanasit; Martin Beer
Journal:  Emerg Infect Dis       Date:  2018-06       Impact factor: 6.883
  7 in total

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