Literature DB >> 1206948

[Diagnosis of myasthenic eye signs. Clinical signs and electronystagmographical findings of saccadic eye movements (author's transl)].

D Schmidt.   

Abstract

The clinical eye signs of 31 myasthenic patients are presented and those signs important for an early diagnosis are then discussed: lid symptoms caused by fatigue (Simpson-test), characteristic lid twitches as well as alternating asymmetrical eye muscle pareses. The importance of an investigation with the tangent scale in the course of which tensilon is injected is pointed out. False diagnosis and differential diagnostic signs are then considered (disseminated sclerosis, aneeurysm, encephalitis, pseudopulbarparalysis). - Our electronystagmographical investigations of saccadic eye movements showed hypometric, alternating saccades with occasional nystagmuslike jerks. After Tensilon injection hypermetric saccades (overshoots) were observed which depended on a disproportion of the supranuclear oculomotor centers and the eye muscles. The "muscleparetic" nystagmus is a pathologically increased endposition nystagmus. The hypometric nystagmuslike jerks during a saccadic eye movement are caused by insufficient phasic innervation.

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Year:  1975        PMID: 1206948

Source DB:  PubMed          Journal:  Klin Monbl Augenheilkd        ISSN: 0023-2165            Impact factor:   0.700


  3 in total

1.  Alterations of saccadic eye movements in myotonic dystrophy.

Authors:  M R Koca; F Horn; M Korth
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1992       Impact factor: 3.117

2.  The ocular signs and symptoms of myasthenia gravis.

Authors:  H J Oosterhuis
Journal:  Doc Ophthalmol       Date:  1982-01-29       Impact factor: 2.379

3.  [Idiopathic blepharospasm. Clinical and electrophysiological investigations in 27 patients (author's transl)].

Authors:  E Schenck; D Schmidt
Journal:  Arch Psychiatr Nervenkr (1970)       Date:  1978-12-14
  3 in total

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