AIM: To identify antenatal and intrapartum factors contributing to the aetiology of cerebral palsy (CP). METHODS: A case-control study using moderate/severe cases of cerebral palsy identified from the Victorian Cerebral Palsy Register and two controls per case identified through the Victorian Perinatal Data Collection Unit. RESULTS: A number of previously identified risk factors for CP were confirmed in our data. New observations were (in specific sub-groups): protective effects of mother's negative Rhesus status, cigarette smoking at the first visit and episiotomy and an increased risk of CP associated with an abnormal antenatal cardiotocograph. CONCLUSIONS: Although the result of the deliberate investigation of specific aspects of the antenatal and intrapartum period identified from a pilot study, our new findings must be interpreted with caution as they were not all based on specific a priori hypotheses, although some had been examined by other investigators. We would encourage their evaluation in other data sets.
AIM: To identify antenatal and intrapartum factors contributing to the aetiology of cerebral palsy (CP). METHODS: A case-control study using moderate/severe cases of cerebral palsy identified from the Victorian Cerebral Palsy Register and two controls per case identified through the Victorian Perinatal Data Collection Unit. RESULTS: A number of previously identified risk factors for CP were confirmed in our data. New observations were (in specific sub-groups): protective effects of mother's negative Rhesus status, cigarette smoking at the first visit and episiotomy and an increased risk of CP associated with an abnormal antenatal cardiotocograph. CONCLUSIONS: Although the result of the deliberate investigation of specific aspects of the antenatal and intrapartum period identified from a pilot study, our new findings must be interpreted with caution as they were not all based on specific a priori hypotheses, although some had been examined by other investigators. We would encourage their evaluation in other data sets.
Authors: Tess C Lang; Elena Fuentes-Afflick; William M Gilbert; Thomas B Newman; Guibo Xing; Yvonne W Wu Journal: Pediatrics Date: 2012-03-19 Impact factor: 7.124
Authors: Jelske W van der Burg; Sarbattama Sen; Virginia R Chomitz; Jaap C Seidell; Alan Leviton; Olaf Dammann Journal: Pediatr Res Date: 2015-09-16 Impact factor: 3.756
Authors: Mary D Crisham Janik; Thomas B Newman; Yvonne W Cheng; Guibo Xing; William M Gilbert; Yvonne W Wu Journal: J Pediatr Date: 2013-08-06 Impact factor: 4.406
Authors: Jelske W van der Burg; T Michael O'Shea; Karl Kuban; Elizabeth N Allred; Nigel Paneth; Olaf Dammann; Alan Leviton Journal: J Child Neurol Date: 2018-01-11 Impact factor: 1.987