Literature DB >> 12067611

One gene and one outcome? No way.

Stephen Chanock1, Sholom Wacholder.   

Abstract

The world of molecular diagnostics is undergoing major change because of both technical advances and the availability of rapidly expanding genetic databases generated by the study of human genomics. These resources comprise an extraordinary opportunity to decipher the biological importance of genetic aberrations, and link our understanding with clinical utility. The challenge lies in sorting through the information and developing effective strategies to advance molecular diagnostics.

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Year:  2002        PMID： 12067611     DOI： 10.1016/s1471-4914(02)02356-0

Source DB:  PubMed          Journal:  Trends Mol Med        ISSN： 1471-4914            Impact factor:   11.951


  6 in total

1.  Psychiatric genetics: what to expect.

Authors:  Joachim F Hallmayer
Journal:  Curr Psychiatry Rep       Date:  2004-06       Impact factor: 5.285

2.  Informed decision making about predictive DNA tests: arguments for more public visibility of personal deliberations about the good life.

Authors:  Marianne Boenink; Simone van der Burg
Journal:  Med Health Care Philos       Date:  2010-05

Review 3.  Reproducibility and specificity concerns associated with nucleic acid amplification tests for detecting Chlamydia trachomatis.

Authors:  A Hadgu; M Sternberg
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2008-07-19       Impact factor: 3.267

4.  Predicting diabetic nephropathy using a multifactorial genetic model.

Authors:  Ilana Blech; Mark Katzenellenbogen; Alexandra Katzenellenbogen; Julio Wainstein; Ardon Rubinstein; Ilana Harman-Boehm; Joseph Cohen; Toni I Pollin; Benjamin Glaser
Journal:  PLoS One       Date:  2011-04-14       Impact factor: 3.240

5.  Molecular medicine and concepts of disease: the ethical value of a conceptual analysis of emerging biomedical technologies.

Authors:  Marianne Boenink
Journal:  Med Health Care Philos       Date:  2010-02

6.  Manganese superoxide dismutase Ala-9Val polymorphism and risk of breast cancer in a population-based case-control study of African Americans and whites.

Authors:  Robert C Millikan; Jon Player; Allan René de Cotret; Patricia Moorman; Gary Pittman; Vani Vannappagari; Chiu-Kit J Tse; Temitope Keku
Journal:  Breast Cancer Res       Date:  2004-04-07       Impact factor: 6.466
  6 in total

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