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Literature DB >> 1206752

Tumor suppression by a lymphokine released into the circulation of mice with delayed hypersensitivity.

S B Salvin, J S Youngner, J Nishio, R Neta.

Abstract

Lymphokines such as migration inhibitory factor and type II interferon were released into the circulation of tuberculin-sensitive mice after iv injection of old tuberculin. Daily administration of such sera into the tumor sites of mice given implants of sarcoma MC-36 markedly suppressed tumor growth.

Entities: Chemical Disease Species

Mesh：

Substances：
Lymphokines

Year: 1975 PMID： 1206752 DOI： 10.1093/jnci/55.5.1233

Source DB: PubMed Journal: J Natl Cancer Inst ISSN： 0027-8874 Impact factor: 13.506

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Cited

13 in total

Review 1. Interferons 1992. How much of the promise has been realised?

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Journal: Drugs Date: 1992-03 Impact factor: 9.546

2. Utility of interferons in clinical radiotherapy.

Authors: K L Mossman; L T Hill; A Dritschilo
Journal: J Natl Med Assoc Date: 1982-11 Impact factor: 1.798

Review 3. Macrophage-mediated destruction of malignant tumor cells and new strategies for the therapy of metastatic disease.

Authors: I J Fidler; G Poste
Journal: Springer Semin Immunopathol Date: 1982

4. Interferon gamma and granulocyte/macrophage colony-stimulating factor inhibit growth and induce antigens characteristic of myeloid differentiation in small-cell lung cancer cell lines.

Authors: M R Ruff; W L Farrar; C B Pert
Journal: Proc Natl Acad Sci U S A Date: 1986-09 Impact factor: 11.205

5. Cytostasis of different tumours by a murine PPD-reactive CD4+ T lymphocyte clone is mediated by interferon-gamma and tumour necrosis factor alone or synergistically.

Authors: M G Wing; A M Montgomery; C Harley; P J Lachmann
Journal: Clin Exp Immunol Date: 1990-11 Impact factor: 4.330

Tumor suppression by a lymphokine released into the circulation of mice with delayed hypersensitivity.

Review 1. Interferons 1992. How much of the promise has been realised?

2. Utility of interferons in clinical radiotherapy.

Review 3. Macrophage-mediated destruction of malignant tumor cells and new strategies for the therapy of metastatic disease.

4. Interferon gamma and granulocyte/macrophage colony-stimulating factor inhibit growth and induce antigens characteristic of myeloid differentiation in small-cell lung cancer cell lines.

5. Cytostasis of different tumours by a murine PPD-reactive CD4+ T lymphocyte clone is mediated by interferon-gamma and tumour necrosis factor alone or synergistically.

6. Suppression of babesiosis in BCG-infected mice and its correlation with tumor inhibition.

7. Impaired interferon-alpha production in whole-blood cultures from bladder cancer patients.

8. Monocyte and interferon based therapy for the treatment of ovarian cancer.

9. Induction of tumor growth inhibitory factor (TGIF) in human mononuclear cells by OK-432, a streptococcal preparation.

10. Large-scale production and physicochemical characterization of human immune interferon.