OBJECTIVE: The purpose of this study was to investigate the efficacy of continuous local anesthetic infusion system for pain control after cesarean delivery. STUDY DESIGN: This was a randomized prospective double-blind study. Patients who underwent cesarean delivery had a pain system implanted subcutaneously after closure of the fascia. Patients were randomized to receive an infusion of either 0.25% bupivacaine (n = 20) or normal saline solution (n = 16) into the wound for 48 hours. Postoperative pain (determined with a visual analog scale) and postoperative morphine use were assessed at 12, 24, and 48 hours. RESULTS: There were no significant differences in patient demographics or visual analog pain scores at any time interval between the bupivacaine versus the placebo group. However, narcotic requirements to produce this amount of pain relief were significantly less in patients who received bupivacaine infusion rather than normal saline solution at all time intervals. CONCLUSION: The continuous local anesthetic infusion system appears to be effective in reducing postoperative morphine use after cesarean delivery.
RCT Entities:
OBJECTIVE: The purpose of this study was to investigate the efficacy of continuous local anesthetic infusion system for pain control after cesarean delivery. STUDY DESIGN: This was a randomized prospective double-blind study. Patients who underwent cesarean delivery had a pain system implanted subcutaneously after closure of the fascia. Patients were randomized to receive an infusion of either 0.25% bupivacaine (n = 20) or normal saline solution (n = 16) into the wound for 48 hours. Postoperative pain (determined with a visual analog scale) and postoperative morphine use were assessed at 12, 24, and 48 hours. RESULTS: There were no significant differences in patient demographics or visual analog pain scores at any time interval between the bupivacaine versus the placebo group. However, narcotic requirements to produce this amount of pain relief were significantly less in patients who received bupivacaine infusion rather than normal saline solution at all time intervals. CONCLUSION: The continuous local anesthetic infusion system appears to be effective in reducing postoperative morphine use after cesarean delivery.
Authors: Lourdes Ferreira Laso; Amanda López Picado; Fernando Antoñanzas Villar; Laura Lamata de la Orden; Mar Ceballos Garcia; Carolina Ibañez López; Lorena Pipaon Ruilope; Felix Lamata Hernandez; Cesar Valero Martinez; Felipe Aizpuru; Roberto Hernandez Chaves Journal: Clin Drug Investig Date: 2015-09 Impact factor: 2.859
Authors: Gill Norman; Ross A Atkinson; Tanya A Smith; Ceri Rowlands; Amber D Rithalia; Emma J Crosbie; Jo C Dumville Journal: Cochrane Database Syst Rev Date: 2017-10-30
Authors: Sean M Stokes; Elliot Wakeam; Mara B Antonoff; Leah M Backhus; Robert A Meguid; David Odell; Thomas K Varghese Journal: J Thorac Dis Date: 2019-03 Impact factor: 2.895
Authors: Dawn Chung; Yoo Jin Lee; Mi Hyun Jo; Hyun Jong Park; Ga Won Lim; Hanbyoul Cho; Eun Ji Nam; Sang Wun Kim; Jae Hoon Kim; Young Tae Kim; Sunghoon Kim Journal: Obstet Gynecol Sci Date: 2013-03-12