Literature DB >> 12064524

Protein separation using membrane chromatography: opportunities and challenges.

Raja Ghosh1.   

Abstract

Some of the problems associated with packed bed chromatography can be overcome by using synthetic macroporous and microporous membranes as chromatographic media. This paper reviews the current state of development in the area of membrane chromatographic separation of proteins. The transport phenomenon of membrane chromatography is briefly discussed and work done in this area is reviewed. The various separation chemistries which have been utilised for protein separation, along with different applications, are also reviewed. The technical challenges facing membrane chromatography are highlighted and the scope for future work is discussed.

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Year:  2002        PMID： 12064524     DOI： 10.1016/s0021-9673(02)00057-2

Source DB:  PubMed          Journal:  J Chromatogr A        ISSN： 0021-9673            Impact factor:   4.759


  27 in total

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7.  Protein purification with polymeric affinity membranes containing functionalized poly(acid) brushes.

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8.  Dynamic Electrochemical Membranes for Continuous Affinity Protein Separation.

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9.  Para-aminobenzamidine linked regenerated cellulose membranes for plasminogen activator purification: effect of spacer arm length and ligand density.

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10.  Overloading ion-exchange membranes as a purification step for monoclonal antibodies.

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