H J Wittsack1, A Ritzl, U Mödder. 1. Institut für Diagnostische Radiologie, Universität Düsseldorf, Germany. wittsack@uni-duesseldorf.de
Abstract
PURPOSE: Quick and user-friendly analysis of perfusion and diffusion weighted MRI by means of interactive computer software. METHOD: A Windows(R)-based software was developed for analysis of perfusion (PWI) and diffusion (DWI) MR imaging. The computer program was developed in the programming language C++ using optimized algorithms, so that a high computing speed on Win95/98/NT systems is achieved. The established SVD algorithms of Østergaard et al. for quantitative perfusion analysis were implemented. RESULTS: Perfusion parameter maps of the cerebral blood flow (rCBF), the mean transit time (MTT) and the cerebral blood volume (rCBV) in consideration of the arterial input function (AIF) can be calculated and visualized using color tables. Additionally, the calculation of "time-to-peak" maps (TTP) and of maps of the percentage change in signal intensity (PC) is possible. The analysis of n = 10 normal persons shows perfusion values that agree with those found in the literature. DISCUSSION: With the computer program developed here color-coded perfusion parameter maps can be calculated easily. Because of the high computing speed it is possible to get information about tissue perfusion on the basis of the large MR data sets even in acute investigations.
PURPOSE: Quick and user-friendly analysis of perfusion and diffusion weighted MRI by means of interactive computer software. METHOD: A Windows(R)-based software was developed for analysis of perfusion (PWI) and diffusion (DWI) MR imaging. The computer program was developed in the programming language C++ using optimized algorithms, so that a high computing speed on Win95/98/NT systems is achieved. The established SVD algorithms of Østergaard et al. for quantitative perfusion analysis were implemented. RESULTS: Perfusion parameter maps of the cerebral blood flow (rCBF), the mean transit time (MTT) and the cerebral blood volume (rCBV) in consideration of the arterial input function (AIF) can be calculated and visualized using color tables. Additionally, the calculation of "time-to-peak" maps (TTP) and of maps of the percentage change in signal intensity (PC) is possible. The analysis of n = 10 normal persons shows perfusion values that agree with those found in the literature. DISCUSSION: With the computer program developed here color-coded perfusion parameter maps can be calculated easily. Because of the high computing speed it is possible to get information about tissue perfusion on the basis of the large MR data sets even in acute investigations.
Authors: Vince I Madai; Andreas Altaner; Katharina L Stengl; Olivier Zaro-Weber; Wolf Dieter Heiss; Federico C von Samson-Himmelstjerna; Jan Sobesky Journal: J Cereb Blood Flow Metab Date: 2011-03-09 Impact factor: 6.200
Authors: Frank G Zöllner; Gerald Weisser; Marcel Reich; Sven Kaiser; Stefan O Schoenberg; Steven P Sourbron; Lothar R Schad Journal: J Digit Imaging Date: 2013-04 Impact factor: 4.056
Authors: Francesco Cicone; Christian P Filss; Giuseppe Minniti; Camilla Rossi-Espagnet; Annalisa Papa; Claudia Scaringi; Norbert Galldiks; Alessandro Bozzao; N Jon Shah; Francesco Scopinaro; Karl-Josef Langen Journal: Eur J Nucl Med Mol Imaging Date: 2015-03-07 Impact factor: 9.236
Authors: Antoine Verger; Christian P Filss; Philipp Lohmann; Gabriele Stoffels; Michael Sabel; Hans J Wittsack; Elena Rota Kops; Norbert Galldiks; Gereon R Fink; Nadim J Shah; Karl-Josef Langen Journal: Eur J Nucl Med Mol Imaging Date: 2017-08-22 Impact factor: 9.236
Authors: Frank G Zöllner; Markus Daab; Steven P Sourbron; Lothar R Schad; Stefan O Schoenberg; Gerald Weisser Journal: BMC Med Imaging Date: 2016-01-14 Impact factor: 1.930