Literature DB >> 12062427

Zinc is required for structural stability of the C-terminus of archaeal translation initiation factor aIF2beta.

Pablo Gutiérrez1, Stéphane Coillet-Matillon, Cheryl Arrowsmith, Kalle Gehring.   

Abstract

aIF2beta is an archaeal homolog of eukaryotic translation factor eIF2beta necessary for translation initiation and involved in recognition of the initiation codon. In the present study, we demonstrate for the first time zinc binding to the C2-C2 zinc finger at the C-terminus of aIF2beta. Nuclear magnetic resonance backbone assignments were also determined and the secondary structural elements identified.

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Year:  2002        PMID： 12062427     DOI： 10.1016/s0014-5793(02)02610-8

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  4 in total

1.  Structure of the archaeal translation initiation factor aIF2 beta from Methanobacterium thermoautotrophicum: implications for translation initiation.

Authors:  Pablo Gutiérrez; Michael J Osborne; Nadeem Siddiqui; Jean-François Trempe; Cheryl Arrowsmith; Kalle Gehring
Journal:  Protein Sci       Date:  2004-03       Impact factor: 6.725

2.  Structure of archaeal translational initiation factor 2 betagamma-GDP reveals significant conformational change of the beta-subunit and switch 1 region.

Authors:  Masaaki Sokabe; Min Yao; Naoki Sakai; Shingo Toya; Isao Tanaka
Journal:  Proc Natl Acad Sci U S A       Date:  2006-08-21       Impact factor: 11.205

3.  Functional definition and global regulation of Zur, a zinc uptake regulator in a Streptococcus suis serotype 2 strain causing streptococcal toxic shock syndrome.

Authors:  Youjun Feng; Ming Li; Huimin Zhang; Beiwen Zheng; Huiming Han; Changjun Wang; Jinghua Yan; Jiaqi Tang; George F Gao
Journal:  J Bacteriol       Date:  2008-08-22       Impact factor: 3.490

4.  Identification of Plasmodium falciparum Translation Initiation eIF2β Subunit: Direct Interaction with Protein Phosphatase Type 1.

Authors:  Géraldine Tellier; Astrid Lenne; Katia Cailliau-Maggio; Alejandro Cabezas-Cruz; James J Valdés; Alain Martoriati; El M Aliouat; Pierre Gosset; Baptiste Delaire; Aline Fréville; Christine Pierrot; Jamal Khalife
Journal:  Front Microbiol       Date:  2016-05-26       Impact factor: 5.640
  4 in total

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