Literature DB >> 12061547

Radamycin, a novel thiopeptide produced by streptomyces sp. RSP9. II. Physico-chemical properties and structure determination.

Julián Castro Rodríguez1, Gloria González Holgado, Ramón I Santamaría Sánchez, Librada M Cañedo.   

Abstract

The new cyclic peptide antibiotic, radamycin (1) and the known thiopeptide methylsulfomycin I (2) have been isolated from the fermentation broth of a Streptomyces sp. RSP9. The structure of radamycin was elucidated by NMR, LC-MS and FAB-MS and was established as a thiopeptide with oxazole and thiazole moieties, and several unusual amino acids.

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Year:  2002        PMID: 12061547     DOI: 10.7164/antibiotics.55.391

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  4 in total

Review 1.  YcaO-Dependent Posttranslational Amide Activation: Biosynthesis, Structure, and Function.

Authors:  Brandon J Burkhart; Christopher J Schwalen; Greg Mann; James H Naismith; Douglas A Mitchell
Journal:  Chem Rev       Date:  2017-03-03       Impact factor: 60.622

2.  Thiazole-amino acids: influence of thiazole ring on conformational properties of amino acid residues.

Authors:  Monika Staś; Małgorzata A Broda; Dawid Siodłak
Journal:  Amino Acids       Date:  2021-04-10       Impact factor: 3.520

Review 3.  α,β-Dehydroamino acids in naturally occurring peptides.

Authors:  Dawid Siodłak
Journal:  Amino Acids       Date:  2014-10-17       Impact factor: 3.520

4.  Litoralimycins A and B, New Cytotoxic Thiopeptides from Streptomonospora sp. M2.

Authors:  Shadi Khodamoradi; Marc Stadler; Joachim Wink; Frank Surup
Journal:  Mar Drugs       Date:  2020-05-26       Impact factor: 5.118

  4 in total

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