Literature DB >> 12061404

Transferability of HIV by arthropods supports the hypothesis about transmission of the virus from apes to man.

Manfred Eigen1, Werner J Kloft, Gerhard Brandner.   

Abstract

The primate Pan troglodytes troglodytes, a chimpanzee subspecies, has recently been defined as a natural animal host of the human immunodeficiency virus (HIV). Apes are traditionally hunted in Africa and are offered for sale in open-air meat markets. The bloody carcasses are regularly covered with blood-feeding flies, amongst them possibly the stable fly (Stomoxvs calcitrans L.). a cosmopolitically occurring biting fly. This fly is the effective vector for the retrovirus causing equine infectious anemia [corrected]. According to laboratory experiments, the infectivity of ingested HIV is not reduced in the regurgitates of this fly. These findings are combined to explain the mechanism for a possible primary transmission of HIV from ape to man.

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Year:  2002        PMID: 12061404     DOI: 10.1007/s00114-002-0319-x

Source DB:  PubMed          Journal:  Naturwissenschaften        ISSN: 0028-1042


  2 in total

1.  An immunoglobulin binding protein (antigen 5) of the stable fly (Diptera: Muscidae) salivary gland stimulates bovine immune responses.

Authors:  M Ameri; X Wang; M J Wilkerson; M R Kanost; A B Broce
Journal:  J Med Entomol       Date:  2008-01       Impact factor: 2.278

2.  Why is HIV not vector-borne?

Authors:  Troy Day; Nicole Mideo; Samuel Alizon
Journal:  Evol Appl       Date:  2008-01-09       Impact factor: 5.183

  2 in total

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