| Literature DB >> 12060481 |
Cristina Mecucci1, Roberto Rosati, Roberta La Starza.
Abstract
Understanding genomic events and the cascade of their effects in cell function is crucial for identifying distinct subsets of acute myeloid leukemia and developing new therapeutic strategies. Conventional cytogenetics, fluorescence in situ hybridization investigations and molecular studies have provided much information over the past few years. This review will focus on major genomic mechanisms in acute myeloid luekemia and on the genes implicated in the pathogenesis of specific subtypes.Entities:
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Year: 2002 PMID： 12060481 DOI： 10.1046/j.1468-0734.2002.00060.x
Source DB: PubMed Journal: Rev Clin Exp Hematol ISSN： 1127-0020