Literature DB >> 12059194

Proton coupling to [4Fe-4S](2+/+) and [4Fe-4Se](2+/+) oxidation and reduction in a designed protein.

Michelle L Kennedy1, Brian R Gibney.   

Abstract

The coupling of a single proton to [4Fe-4S]2+/+ oxidation/reduction in a de novo designed iron-sulfur protein maquette is presented. The reduced state pKared is 9.3, and the oxidized state pKaox is <6.5. The reduced state pKared shifts to 8.3 upon incorporation of a [4Fe-4Se]2+/+ cluster, implicating the cluster itself or its primary coordination sphere as the proton-coupling site.

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Year:  2002        PMID： 12059194     DOI： 10.1021/ja0171613

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  7 in total

1.  Cubane-type Fe4S4 clusters with chiral thiolate ligation: formation by ligand substitution, detection of intermediates by 1H NMR, and solid state structures including spontaneous resolution upon crystallization.

Authors:  Wayne Lo; Shaw Huang; Shao-Liang Zheng; R H Holm
Journal:  Inorg Chem       Date:  2011-09-26       Impact factor: 5.165

Review 2.  Metalloproteins containing cytochrome, iron-sulfur, or copper redox centers.

Authors:  Jing Liu; Saumen Chakraborty; Parisa Hosseinzadeh; Yang Yu; Shiliang Tian; Igor Petrik; Ambika Bhagi; Yi Lu
Journal:  Chem Rev       Date:  2014-04-23       Impact factor: 60.622

3.  De Novo Construction of Redox Active Proteins.

Authors:  C C Moser; M M Sheehan; N M Ennist; G Kodali; C Bialas; M T Englander; B M Discher; P L Dutton
Journal:  Methods Enzymol       Date:  2016-07-11       Impact factor: 1.600

4.  Incorporating electron-transfer functionality into synthetic metalloproteins from the bottom-up.

Authors:  Jing Hong; Olesya A Kharenko; Michael Y Ogawa
Journal:  Inorg Chem       Date:  2006-12-11       Impact factor: 5.165

5.  Radical S-adenosylmethionine maquette chemistry: Cx3Cx2C peptide coordinated redox active [4Fe-4S] clusters.

Authors:  Amanda Galambas; Jacquelyn Miller; Morgan Jones; Elizabeth McDaniel; Molly Lukes; Hope Watts; Valérie Copié; Joan B Broderick; Robert K Szilagyi; Eric M Shepard
Journal:  J Biol Inorg Chem       Date:  2019-09-05       Impact factor: 3.358

Review 6.  Proton coupled electron transfer and redox active tyrosines in Photosystem II.

Authors:  Bridgette A Barry
Journal:  J Photochem Photobiol B       Date:  2011-03-17       Impact factor: 6.252

7.  De novo metalloprotein design.

Authors:  Matthew J Chalkley; Samuel I Mann; William F DeGrado
Journal:  Nat Rev Chem       Date:  2021-12-06       Impact factor: 34.571
  7 in total

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