| Literature DB >> 12059182 |
Kazuhiko Nakatani1, Chikara Dohno, Isao Saito.
Abstract
We have shown here that (1) substitution of an exocyclic amino group of dG is effective in modulating the chemical properties of dG toward one-electron oxidation and (2) decomposition of the guanine radical cation was effectively suppressed near dPhG. These results indicate that dPhG is a prototype of nucleosides functioning as an intrinsic antioxidant of duplex DNA toward one-electron oxidation.Entities:
Mesh：
Substances：
Year: 2002 PMID： 12059182 DOI： 10.1021/ja025781d
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419