Literature DB >> 12057681

Microbial transformation of alkaloids.

Deborah A Rathbone1, Neil C Bruce.   

Abstract

Alkaloids continue to provide mankind with a plethora of medicines, poisons and potions. Because many valuable drugs are derived from such natural compounds, there is much interest in their transformation to provide new compounds or intermediates for the synthesis of new or improved drugs. This review aims to provide a survey of alkaloid transformations, and concerns microbial transformations and microbially expressed recombinant plant enzymes and their biotechnological applications.

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Year:  2002        PMID： 12057681     DOI： 10.1016/s1369-5274(02)00317-x

Source DB:  PubMed          Journal:  Curr Opin Microbiol        ISSN： 1369-5274            Impact factor:   7.934


  15 in total

Review 1.  Engineering Saccharomyces cerevisiae to produce plant benzylisoquinoline alkaloids.

Authors:  Jianing Han; Yinan Wu; Yilun Zhou; Sijin Li
Journal:  Abiotech       Date:  2021-07-18

2.  Metabolism and resistance of Fusarium spp. to the manzamine alkaloids via a putative retro pictet-spengler reaction and utility of the rational design of antimalarial and antifungal agents.

Authors:  Noer Kasanah; Lorelei Lucas Farr; Abbas Gholipour; David E Wedge; Mark T Hamann
Journal:  Mar Biotechnol (NY)       Date:  2014-02-20       Impact factor: 3.619

3.  Microbial production of plant benzylisoquinoline alkaloids.

Authors:  Hiromichi Minami; Ju-Sung Kim; Nobuhiro Ikezawa; Tomoya Takemura; Takane Katayama; Hidehiko Kumagai; Fumihiko Sato
Journal:  Proc Natl Acad Sci U S A       Date:  2008-05-20       Impact factor: 11.205

4.  Responses of fungi to tropane alkaloids produced by a medicinal plant Hyoscyamus muticus (Egyptian henbane).

Authors:  F F Abdel-Motaal; M S M Nassar; S A El-Zayat; M A El-Sayed; S Ito
Journal:  Folia Microbiol (Praha)       Date:  2009-08-02       Impact factor: 2.099

5.  Biotransformation of natural and synthetic isoflavonoids by two recombinant microbial enzymes.

Authors:  Michael Seeger; Myriam González; Beatriz Cámara; Liliana Muñoz; Emilio Ponce; Lorenzo Mejías; Carolina Mascayano; Yesseny Vásquez; Silvia Sepúlveda-Boza
Journal:  Appl Environ Microbiol       Date:  2003-09       Impact factor: 4.792

6.  Codeine-binding RNA aptamers and rapid determination of their binding constants using a direct coupling surface plasmon resonance assay.

Authors:  Maung Nyan Win; Joshua S Klein; Christina D Smolke
Journal:  Nucleic Acids Res       Date:  2006-10-11       Impact factor: 16.971

Review 7.  Alkaloids in Contemporary Drug Discovery to Meet Global Disease Needs.

Authors:  Sharna-Kay Daley; Geoffrey A Cordell
Journal:  Molecules       Date:  2021-06-22       Impact factor: 4.411

8.  Engineering microbial cells for the biosynthesis of natural compounds of pharmaceutical significance.

Authors:  Philippe Jeandet; Yann Vasserot; Thomas Chastang; Eric Courot
Journal:  Biomed Res Int       Date:  2013-04-27       Impact factor: 3.411

9.  Expression of Brugmansia candida Hyoscyamine 6beta-Hydroxylase gene in Saccharomyces cerevisiae and its potential use as biocatalyst.

Authors:  Alejandra B Cardillo; Julián Rodríguez Talou; Ana M Giulietti
Journal:  Microb Cell Fact       Date:  2008-05-27       Impact factor: 5.328

Review 10.  Current status on biochemistry and molecular biology of microbial degradation of nicotine.

Authors:  Raman Gurusamy; Sakthivel Natarajan
Journal:  ScientificWorldJournal       Date:  2013-12-29
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