Literature DB >> 12057130

New drugs in gynecologic cancer.

A Daud1, P Munster, P Munster, D R Spriggs.   

Abstract

The implementation of new drug treatments has improved the prognosis for advanced cancers of the cervix, uterus, and ovary. Platinum analogs are the most effective drugs in the treatment of ovarian cancer. Other drugs, such as oxaliplatin, have been proposed as a rational treatment of platinum refractory ovarian cancer. Epothilones are also being studied in clinical trials, as are histone deacetylase inhibitors. Several promising agents may soon receive Food and Drug Administration approval.

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Year:  2001        PMID: 12057130     DOI: 10.1007/s11864-001-0054-0

Source DB:  PubMed          Journal:  Curr Treat Options Oncol        ISSN: 1534-6277


  30 in total

Review 1.  Development of inhibitors for protein tyrosine kinases.

Authors:  F A Al-Obeidi; K S Lam
Journal:  Oncogene       Date:  2000-11-20       Impact factor: 9.867

2.  The role of DNA mismatch repair in platinum drug resistance.

Authors:  D Fink; S Nebel; S Aebi; H Zheng; B Cenni; A Nehmé; R D Christen; S B Howell
Journal:  Cancer Res       Date:  1996-11-01       Impact factor: 12.701

Review 3.  Oxaliplatin in ovarian cancer.

Authors:  C Sessa; W W ten Bokkel Huinink; A du Bois
Journal:  Ann Oncol       Date:  1999       Impact factor: 32.976

4.  The proteasome inhibitor PS-341 in cancer therapy.

Authors:  B A Teicher; G Ara; R Herbst; V J Palombella; J Adams
Journal:  Clin Cancer Res       Date:  1999-09       Impact factor: 12.531

Review 5.  Herceptin (trastuzamab) in advanced breast cancer.

Authors:  J Stebbing; E Copson; S O'Reilly
Journal:  Cancer Treat Rev       Date:  2000-08       Impact factor: 12.111

Review 6.  Epidermal growth factor receptor inhibition by a monoclonal antibody as anticancer therapy.

Authors:  J Mendelsohn
Journal:  Clin Cancer Res       Date:  1997-12       Impact factor: 12.531

7.  Oxaliplatin or paclitaxel in patients with platinum-pretreated advanced ovarian cancer: A randomized phase II study of the European Organization for Research and Treatment of Cancer Gynecology Group.

Authors:  M J Piccart; J A Green; A J Lacave; N Reed; I Vergote; P Benedetti-Panici; A Bonetti; V Kristeller-Tome; C M Fernandez; D Curran; M Van Glabbeke; D Lacombe; M C Pinel; S Pecorelli
Journal:  J Clin Oncol       Date:  2000-03       Impact factor: 44.544

8.  Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase.

Authors:  R P Warrell; L Z He; V Richon; E Calleja; P P Pandolfi
Journal:  J Natl Cancer Inst       Date:  1998-11-04       Impact factor: 13.506

9.  Inhibition of the oncogene product p185erbB-2 in vitro and in vivo by geldanamycin and dihydrogeldanamycin derivatives.

Authors:  R C Schnur; M L Corman; R J Gallaschun; B A Cooper; M F Dee; J L Doty; M L Muzzi; J D Moyer; C I DiOrio; E G Barbacci
Journal:  J Med Chem       Date:  1995-09-15       Impact factor: 7.446

10.  In vitro circumvention of cisplatin resistance by the novel sterically hindered platinum complex AMD473.

Authors:  J Holford; S Y Sharp; B A Murrer; M Abrams; L R Kelland
Journal:  Br J Cancer       Date:  1998       Impact factor: 7.640

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