| Literature DB >> 12056862 |
Sharon Browning1, Brian L Browning.
Abstract
Important methods for calculating likelihoods of genealogical relationships and mapping genes are based on hidden Markov models for the process of identity by descent along chromosomes. The computational time for the algorithms depends critically on the size of the statespace of the hidden Markov model. We describe the maximal grouping together of states of the model to reduce the size of the statespace. This grouping is based on pedigree symmetries. We also present an efficient algorithm for finding the maximal grouping. Copyright 2002 Elsevier Science (USA).Mesh:
Year: 2002 PMID: 12056862 DOI: 10.1006/tpbi.2002.1583
Source DB: PubMed Journal: Theor Popul Biol ISSN: 0040-5809 Impact factor: 1.570