Brenda K Shelton1. 1. Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD, USA.
Abstract
OBJECTIVES: To provide an overview of colorectal carcinoma (CRC), including current treatment strategies for various stages of the disease. DATA SOURCES: Research articles and textbooks. CONCLUSIONS: Despite screening methods for early detection of CRC, many patients present with late-stage disease and have a poor prognosis. The approval of irinotecan for CRC changed the approach to treatment, and there are numerous agents under clinical evaluation that may soon be available for the management of patients with CRC. IMPLICATIONS FOR NURSING PRACTICE: Recent advances in molecular targeting have led to the development of new treatments for CRC. Because nurses will ultimately administer these agents, it is important to understand how these agents target CRC.
OBJECTIVES: To provide an overview of colorectal carcinoma (CRC), including current treatment strategies for various stages of the disease. DATA SOURCES: Research articles and textbooks. CONCLUSIONS: Despite screening methods for early detection of CRC, many patients present with late-stage disease and have a poor prognosis. The approval of irinotecan for CRC changed the approach to treatment, and there are numerous agents under clinical evaluation that may soon be available for the management of patients with CRC. IMPLICATIONS FOR NURSING PRACTICE: Recent advances in molecular targeting have led to the development of new treatments for CRC. Because nurses will ultimately administer these agents, it is important to understand how these agents target CRC.
Authors: H G Zhang; X W Xu; X P Shi; B W Han; Z H Li; W H Ren; P J Chen; Y F Lou; B Li; X Y Luo Journal: Clin Transl Oncol Date: 2015-09-14 Impact factor: 3.405
Authors: Wael Mahmoud Aboulthana; Noha El-Sayed Ibrahim; Noha Mohamed Osman; Mohamed Mahmoud Seif; Amgad Kamal Hassan; Ahmed Mahmoud Youssef; Amal Mostafa El-Feky; A A Madboli Journal: Asian Pac J Cancer Prev Date: 2020-05-01