Literature DB >> 12053029

Arteriosclerosis of penile arteries: histological findings and their significance in the treatment of erectile dysfunction.

Ulrich Grein1, Günter E Schubert.   

Abstract

OBJECTIVES: In this pathomorphological study, location, distribution, and degree of arteriosclerotic stenoses in penile arteries from unselected cadavers are investigated. The findings are discussed in the context of penile revascularization and may explain the poor results of this form of surgery in older patients with general arteriosclerosis.
MATERIALS AND METHODS: 120 penile specimens from 120 cadavers were examined histologically after van Gieson staining. Transverse sections were performed at the level of the pubic bone, in the middle of the penis, and at the sulcus coronarius. At these levels the dorsal and deep penile arteries were examined.
RESULTS: We found arteriosclerotic stenoses of the penile arteries in 65% of the specimens. Of these stenotic lesions, 20.4% were situated proximally, 37.1% centrally, and 42.5% distally.
CONCLUSIONS: In patients with arteriosclerotic stenoses of the penile arteries, microsurgical penile revascularization to the proximal part of the dorsal arteries at the base of the penis seems to be without any relevant long-lasting hemodynamic effect, because the blood flow will be impeded by the peripheral stenoses. This can explain the poor results of revascularization in this group of patients. Copyright 2002 S. Karger AG, Basel

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Year:  2002        PMID: 12053029     DOI: 10.1159/000058447

Source DB:  PubMed          Journal:  Urol Int        ISSN: 0042-1138            Impact factor:   2.089


  1 in total

1.  Serum Arginase II level can be a novel indicator for erectile dysfunction in patients with vasculogenic erectile dysfunction: a comparative study.

Authors:  Abdel Shakour Abdel Hafez Abdel Wahed; Mohamed Abdel Mawgood Amer; Nagah Mohamed Abou Mohamed; Mohamed Ismael Mobasher; Hassan Mamdouh; Sameh Fayek GamalEl Din; Mohammed Said ElSheemy
Journal:  Int Urol Nephrol       Date:  2018-06-28       Impact factor: 2.370

  1 in total

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