Literature DB >> 12052643

Molecular mechanisms of nickel carcinogenesis.

H Cangul1, L Broday, K Salnikow, J Sutherland, W Peng, Q Zhang, V Poltaratsky, H Yee, M A Zoroddu, M Costa.   

Abstract

Humans are exposed to carcinogenic nickel (Ni) compounds both occupationally and environmentally. In this paper, molecular mechanisms of nickel carcinogenesis are considered from the point-of-view of the uptake of nickel sulfide particles in cells, their dissolution and their effects on heterochromatin. Molecular mechanisms by which nickel induces gene silencing, DNA hypermethylation and inhibition of histone acetylation, will be discussed.

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Year:  2002        PMID： 12052643     DOI： 10.1016/s0378-4274(01)00485-4

Source DB:  PubMed          Journal:  Toxicol Lett        ISSN： 0378-4274            Impact factor:   4.372


  12 in total

1.  Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1.

Authors:  Cynthia C Jose; Lakshmanan Jagannathan; Vinay S Tanwar; Xiaoru Zhang; Chongzhi Zang; Suresh Cuddapah
Journal:  Mol Carcinog       Date:  2018-03-24       Impact factor: 4.784

2.  Nickel stimulates L1 retrotransposition by a post-transcriptional mechanism.

Authors:  Mohammed El-Sawy; Shubha P Kale; Christine Dugan; Thuc Quyen Nguyen; Victoria Belancio; Heather Bruch; Astrid M Roy-Engel; Prescott L Deininger
Journal:  J Mol Biol       Date:  2005-10-04       Impact factor: 5.469

Review 3.  Altering Genomic Integrity: Heavy Metal Exposure Promotes Transposable Element-Mediated Damage.

Authors:  Maria E Morales; Geraldine Servant; Catherine Ade; Astrid M Roy-Engel
Journal:  Biol Trace Elem Res       Date:  2015-03-14       Impact factor: 3.738

4.  Epigenetic dysregulation by nickel through repressive chromatin domain disruption.

Authors:  Cynthia C Jose; Beisi Xu; Lakshmanan Jagannathan; Candi Trac; Ramya K Mallela; Takamitsu Hattori; Darson Lai; Shohei Koide; Dustin E Schones; Suresh Cuddapah
Journal:  Proc Natl Acad Sci U S A       Date:  2014-09-22       Impact factor: 11.205

5.  Heavy metals stimulate human LINE-1 retrotransposition.

Authors:  Shubha P Kale; Lakisha Moore; Prescott L Deininger; Astrid M Roy-Engel
Journal:  Int J Environ Res Public Health       Date:  2005-04       Impact factor: 3.390

6.  Nuclear factor erythroid 2 - related factor 2 and its relationship with cellular response in nickel exposure: a systems biology analysis.

Authors:  Luisa Jiménez-Vidal; Pedro Espitia-Pérez; José Torres-Ávila; Dina Ricardo-Caldera; Shirley Salcedo-Arteaga; Claudia Galeano-Páez; Karina Pastor-Sierra; Lyda Espitia-Pérez
Journal:  BMC Pharmacol Toxicol       Date:  2019-12-19       Impact factor: 2.483

7.  Basic research on a cylindrical implant made of shape-memory alloy for the treatment of long bone fracture.

Authors:  Eiji Kawakita; Zhuo Wang; Takaya Kato; Tadashi Inaba; Yuichi Kasai
Journal:  Open Orthop J       Date:  2012-06-29

8.  Nickel ion inhibits nuclear factor-kappa B activity in human oral squamous cell carcinoma.

Authors:  Takashi Shionome; Shigeki Endo; Daisuke Omagari; Masatake Asano; Hitoshi Toyoma; Tomohiko Ishigami; Kazuo Komiyama
Journal:  PLoS One       Date:  2013-07-03       Impact factor: 3.240

9.  Cobalt and nickel stabilize stem cell transcription factor OCT4 through modulating its sumoylation and ubiquitination.

Authors:  Yixin Yao; Yinghua Lu; Wen-Chi Chen; Yongping Jiang; Tao Cheng; Yupo Ma; Lou Lu; Wei Dai
Journal:  PLoS One       Date:  2014-01-31       Impact factor: 3.240

10.  Nickel-Refining Fumes Induced DNA Damage and Apoptosis of NIH/3T3 Cells via Oxidative Stress.

Authors:  Yue Wang; Sheng-Yuan Wang; Li Jia; Lin Zhang; Jing-Chong Ba; Dan Han; Cui-Ping Yu; Yong-Hui Wu
Journal:  Int J Environ Res Public Health       Date:  2016-06-23       Impact factor: 3.390
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