Literature DB >> 12051503

Diagnosis of hyperadrenocorticism in dogs: a survey of internists and dermatologists.

Ellen N Behrend1, Robert J Kemppainen, Terrence P Clark, M D Salman, Mark E Peterson.   

Abstract

OBJECTIVE: To determine testing protocols used by board-certified internists and dermatologists for diagnosis of hyperadrenocorticism (HAC) in dogs.
DESIGN: Survey. STUDY POPULATION: Board-certified internists and dermatologists. PROCEDURE: A questionnaire was mailed to 501 specialists to gather information pertaining to diagnosis of HAC.
RESULTS: 206 surveys were returned. Only 26% of respondents indicated they would screen a dog for HAC if the dog had only a few laboratory abnormalities consistent with HAC and no clinical signs consistent with the disease; 31% indicated they would not, and 43% indicated they would sometimes. Overall, 55% of respondents indicated they preferred to use the low-dose dexamethasone suppression test for routine screening of dogs suspected to have HAC. However, many respondents indicated they would use a different screening test than usual in particular circumstances. Sixty-eight percent of respondents indicated they would perform a second screening test for confirmation if results of an initial screening test were positive but there were few clinical or laboratory abnormalities consistent with HAC. Most respondents used some sort of test to differentiate pituitary-dependent HAC from HAC secondary to an adrenal tumor (AT), but no 1 test was clearly preferred. Ultrasonography was commonly used, whereas computed tomography and magnetic resonance imaging were not, even if available. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that the low-dose dexamethasone suppression test is the test most commonly used to screen dogs for HAC but that other tests may be used in certain circumstances. A variety of tests were used to differentiate pituitary-dependent HAC from HAC secondary to an AT.

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Year:  2002        PMID: 12051503     DOI: 10.2460/javma.2002.220.1643

Source DB:  PubMed          Journal:  J Am Vet Med Assoc        ISSN: 0003-1488            Impact factor:   1.936


  3 in total

Review 1.  Diagnosis and management of geriatric canine endocrine disorders.

Authors:  A Boari; G Aste
Journal:  Vet Res Commun       Date:  2003-09       Impact factor: 2.459

2.  Evaluation of individual low-dose dexamethasone suppression test patterns in naturally occurring hyperadrenocorticism in dogs.

Authors:  Michael Bennaim; Robert E Shiel; Christopher Forde; Carmel T Mooney
Journal:  J Vet Intern Med       Date:  2018-03-02       Impact factor: 3.333

3.  Presumptive iatrogenic hypoadrenocorticism induced by high-dose ketoconazole administration in a dog.

Authors:  Andrea Hernandez-Bures; Amelia G White; Laura Riordan
Journal:  J Vet Intern Med       Date:  2019-08-26       Impact factor: 3.333

  3 in total

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