Literature DB >> 12050401

Nef enhances human immunodeficiency virus type 1 infectivity in the absence of matrix.

Tatyana Dorfman1, Elena Popova, Massimo Pizzato, Heinrich G Göttlinger.   

Abstract

Nef enhances the serine phosphorylation of the human immunodeficiency virus type 1 matrix (MA) protein, which suggests that MA may be a functional target of Nef. Using mutants that remain infectious despite the absence of most or all of MA, we show in the present study that the ability of Nef to enhance virus infectivity is not compromised even if MA is entirely replaced by a heterologous lipid anchor.

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Year:  2002        PMID： 12050401      PMCID： PMC136271          DOI： 10.1128/jvi.76.13.6857-6862.2002

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  56 in total

1.  HIV-1 Nef association with cellular serine kinase correlates with enhanced virion infectivity and efficient proviral DNA synthesis.

Authors:  M Wiskerchen; C Cheng-Mayer
Journal:  Virology       Date:  1996-10-01       Impact factor: 3.616

2.  Identification of a nef allele that causes lymphocyte activation and acute disease in macaque monkeys.

Authors:  Z Du; S M Lang; V G Sasseville; A A Lackner; P O Ilyinskii; M D Daniel; J U Jung; R C Desrosiers
Journal:  Cell       Date:  1995-08-25       Impact factor: 41.582

3.  Producer-cell modification of human immunodeficiency virus type 1: Nef is a virion protein.

Authors:  M W Pandori; N J Fitch; H M Craig; D D Richman; C A Spina; J C Guatelli
Journal:  J Virol       Date:  1996-07       Impact factor: 5.103

4.  Human immunodeficiency virus type 1 Nef associates with a cellular serine kinase in T lymphocytes.

Authors:  E T Sawai; A Baur; H Struble; B M Peterlin; J A Levy; C Cheng-Mayer
Journal:  Proc Natl Acad Sci U S A       Date:  1994-02-15       Impact factor: 11.205

5.  Human immunodeficiency virus type 1 Nef protein is incorporated into virus particles and specifically cleaved by the viral proteinase.

Authors:  R Welker; H Kottler; H R Kalbitzer; H G Kräusslich
Journal:  Virology       Date:  1996-05-01       Impact factor: 3.616

6.  The growth advantage conferred by HIV-1 nef is determined at the level of viral DNA formation and is independent of CD4 downregulation.

Authors:  M Y Chowers; M W Pandori; C A Spina; D D Richman; J C Guatelli
Journal:  Virology       Date:  1995-10-01       Impact factor: 3.616

7.  Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 Nef.

Authors:  M A Goldsmith; M T Warmerdam; R E Atchison; M D Miller; W C Greene
Journal:  J Virol       Date:  1995-07       Impact factor: 5.103

8.  Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients.

Authors:  N J Deacon; A Tsykin; A Solomon; K Smith; M Ludford-Menting; D J Hooker; D A McPhee; A L Greenway; A Ellett; C Chatfield; V A Lawson; S Crowe; A Maerz; S Sonza; J Learmont; J S Sullivan; A Cunningham; D Dwyer; D Dowton; J Mills
Journal:  Science       Date:  1995-11-10       Impact factor: 47.728

9.  Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 Nef protein.

Authors:  O Schwartz; V Maréchal; S Le Gall; F Lemonnier; J M Heard
Journal:  Nat Med       Date:  1996-03       Impact factor: 53.440

10.  Crystal structures of the trimeric human immunodeficiency virus type 1 matrix protein: implications for membrane association and assembly.

Authors:  C P Hill; D Worthylake; D P Bancroft; A M Christensen; W I Sundquist
Journal:  Proc Natl Acad Sci U S A       Date:  1996-04-02       Impact factor: 11.205
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  17 in total

1.  Recent Insights into HIV Accessory Proteins.

Authors:  Jenny L. Anderson; Thomas J. Hope
Journal:  Curr Infect Dis Rep       Date:  2003-10       Impact factor: 3.725

2.  Human immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinase.

Authors:  Pamela Stumptner-Cuvelette; Mabel Jouve; Julie Helft; Marc Dugast; Anne-Sophie Glouzman; Karin Jooss; Graça Raposo; Philippe Benaroch
Journal:  Mol Biol Cell       Date:  2003-09-17       Impact factor: 4.138

Review 3.  HIV accessory proteins and surviving the host cell.

Authors:  Jenny L Anderson; Thomas J Hope
Journal:  Curr HIV/AIDS Rep       Date:  2004-04       Impact factor: 5.071

4.  Human immunodeficiency virus type 1 Nef incorporation into virions does not increase infectivity.

Authors:  Nadine Laguette; Serge Benichou; Stéphane Basmaciogullari
Journal:  J Virol       Date:  2008-11-05       Impact factor: 5.103

5.  HIV-1 Nef responsiveness is determined by Env variable regions involved in trimer association and correlates with neutralization sensitivity.

Authors:  Yoshiko Usami; Heinrich Göttlinger
Journal:  Cell Rep       Date:  2013-10-24       Impact factor: 9.423

6.  The Nef-like effect of murine leukemia virus glycosylated gag on HIV-1 infectivity is mediated by its cytoplasmic domain and depends on the AP-2 adaptor complex.

Authors:  Yoshiko Usami; Sergei Popov; Heinrich G Göttlinger
Journal:  J Virol       Date:  2014-01-08       Impact factor: 5.103

Review 7.  HIV Genome-Wide Protein Associations: a Review of 30 Years of Research.

Authors:  Guangdi Li; Erik De Clercq
Journal:  Microbiol Mol Biol Rev       Date:  2016-06-29       Impact factor: 11.056

8.  Comparative proteomic analysis of HIV-1 particles reveals a role for Ezrin and EHD4 in the Nef-dependent increase of virus infectivity.

Authors:  Christelle Brégnard; Alessia Zamborlini; Marjorie Leduc; Philippe Chafey; Luc Camoin; Ali Saïb; Serge Benichou; Olivier Danos; Stéphane Basmaciogullari
Journal:  J Virol       Date:  2013-01-16       Impact factor: 5.103

9.  Nef and cell signaling transduction: a possible involvement in the pathogenesis of human immunodeficiency virus-associated dementia.

Authors:  Valeria Bergonzini; Arianna Calistri; Cristiano Salata; Claudia Del Vecchio; Elena Sartori; Cristina Parolin; Giogio Palù
Journal:  J Neurovirol       Date:  2009-05       Impact factor: 2.643

10.  Role of human immunodeficiency virus type 1 matrix phosphorylation in an early postentry step of virus replication.

Authors:  Rajnish Kaushik; Lee Ratner
Journal:  J Virol       Date:  2004-03       Impact factor: 5.103
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