Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The human cytomegalovirus US8 glycoprotein binds to major histocompatibility complex class I products.

Literature DB >> 12050396

The human cytomegalovirus US8 glycoprotein binds to major histocompatibility complex class I products.

Abstract

Human cytomegalovirus US8 is a type I membrane protein that partially colocalizes with cellular endosomal and lysosomal proteins. Although US8 does not have discernible effects on the processing and cell surface distribution of major histocompatibility complex (MHC) class I products, we have demonstrated that US8 binds to MHC class I heavy chains in the endoplasmic reticulum.

Entities: Chemical Species

Mesh：

Substances：

Year: 2002 PMID： 12050396 PMCID： PMC136258 DOI： 10.1128/jvi.76.13.6832-6835.2002

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

26 in total

1. The cytosolic tail of class I MHC heavy chain is required for its dislocation by the human cytomegalovirus US2 and US11 gene products.

Authors: C M Story; M H Furman; H L Ploegh
Journal: Proc Natl Acad Sci U S A Date: 1999-07-20 Impact factor: 11.205

Review 2. Viral subversion of the immune system.

Authors: D Tortorella; B E Gewurz; M H Furman; D J Schust; H L Ploegh
Journal: Annu Rev Immunol Date: 2000 Impact factor: 28.527

3. A cytomegalovirus glycoprotein re-routes MHC class I complexes to lysosomes for degradation.

Authors: U Reusch; W Muranyi; P Lucin; H G Burgert; H Hengel; U H Koszinowski
Journal: EMBO J Date: 1999-02-15 Impact factor: 11.598

4. The human cytomegalovirus US6 glycoprotein inhibits transporter associated with antigen processing-dependent peptide translocation.

Authors: P J Lehner; J T Karttunen; G W Wilkinson; P Cresswell
Journal: Proc Natl Acad Sci U S A Date: 1997-06-24 Impact factor: 11.205

5. A viral ER-resident glycoprotein inactivates the MHC-encoded peptide transporter.

Authors: H Hengel; J O Koopmann; T Flohr; W Muranyi; E Goulmy; G J Hämmerling; U H Koszinowski; F Momburg
Journal: Immunity Date: 1997-05 Impact factor: 31.745

6. Human cytomegalovirus immediate early glycoprotein US3 retains MHC class I molecules by transient association.

Authors: A Gruhler; P A Peterson; K Früh
Journal: Traffic Date: 2000-04 Impact factor: 6.215

7. Role of envelope protein gE endocytosis in the pseudorabies virus life cycle.

Authors: R S Tirabassi; L W Enquist
Journal: J Virol Date: 1998-06 Impact factor: 5.103

8. A mouse cytomegalovirus glycoprotein retains MHC class I complexes in the ERGIC/cis-Golgi compartments.

Authors: H Ziegler; R Thale; P Lucin; W Muranyi; T Flohr; H Hengel; H Farrell; W Rawlinson; U H Koszinowski
Journal: Immunity Date: 1997-01 Impact factor: 31.745

9. Human cytomegalovirus US2 destabilizes major histocompatibility complex class I heavy chains.

Authors: T R Jones; L Sun
Journal: J Virol Date: 1997-04 Impact factor: 5.103

10. The immunoevasive function encoded by the mouse cytomegalovirus gene m152 protects the virus against T cell control in vivo.

Authors: A Krmpotic; M Messerle; I Crnkovic-Mertens; B Polic; S Jonjic; U H Koszinowski
Journal: J Exp Med Date: 1999-11-01 Impact factor: 14.307

16 in total

1. Modelling cytomegalovirus replication patterns in the human host: factors important for pathogenesis.

Authors: Roland R Regoes; E Frances Bowen; Alethea V Cope; Dehila Gor; Aycan F Hassan-Walker; H Grant Prentice; Margaret A Johnson; Paul Sweny; Andrew K Burroughs; Paul D Griffiths; Sebastian Bonhoeffer; Vincent C Emery
Journal: Proc Biol Sci Date: 2006-08-07 Impact factor: 5.349

2. Human cytomegalovirus protein pp71 disrupts major histocompatibility complex class I cell surface expression.

Authors: Joanne Trgovcich; Colleen Cebulla; Pete Zimmerman; Daniel D Sedmak
Journal: J Virol Date: 2006-01 Impact factor: 5.103

3. Dislocation of a type I membrane protein requires interactions between membrane-spanning segments within the lipid bilayer.

Authors: Brendan N Lilley; Domenico Tortorella; Hidde L Ploegh
Journal: Mol Biol Cell Date: 2003-06-13 Impact factor: 4.138

4. Evasion of CD8+ T cells is critical for superinfection by cytomegalovirus.

Authors: Scott G Hansen; Colin J Powers; Rebecca Richards; Abigail B Ventura; Julia C Ford; Don Siess; Michael K Axthelm; Jay A Nelson; Michael A Jarvis; Louis J Picker; Klaus Früh
Journal: Science Date: 2010-04-02 Impact factor: 47.728

5. Mutation of glutamine to arginine at position 548 of IE2 86 in human cytomegalovirus leads to decreased expression of IE2 40, IE2 60, UL83, and UL84 and increased transcription of US8-9 and US29-32.

Authors: Sarah W Burgdorf; Charles L Clark; James R Burgdorf; Deborah H Spector
Journal: J Virol Date: 2011-08-24 Impact factor: 5.103

6. Rhesus cytomegalovirus contains functional homologues of US2, US3, US6, and US11.

Authors: Nupur T Pande; Colin Powers; Kwangseog Ahn; Klaus Früh
Journal: J Virol Date: 2005-05 Impact factor: 5.103

7. Human cytomegalovirus disrupts the major histocompatibility complex class I peptide-loading complex and inhibits tapasin gene transcription.

Authors: Anne Halenius; Sebastian Hauka; Lars Dölken; Jan Stindt; Henrike Reinhard; Constanze Wiek; Helmut Hanenberg; Ulrich H Koszinowski; Frank Momburg; Hartmut Hengel
Journal: J Virol Date: 2011-01-19 Impact factor: 5.103