OBJECTIVES: To determine if attention-related changes of hemispheric perfusion increases, as assessed by blood-flow sensitive techniques, are as reliable as language-related hemispheric perfusion increases. METHODS: The reproducibility of hemispheric blood flow velocity increases during a line bisection task was assessed with functional transcranial Doppler sonography. RESULTS: Over repeated examinations, the index of lateralization of 20 healthy subjects showed a high test-retest reproducibility (r=0.9, P<0.01). No practice effects were detected over the course of 10 re-assessments of one subject. CONCLUSIONS: Hemispheric lateralization of visuospatial attention is a robust phenomenon and can be reliably determined using perfusion sensitive measurements. Future studies should focus on investigating lesion-related reorganization of attentional processing with blood-flow sensitive techniques.
OBJECTIVES: To determine if attention-related changes of hemispheric perfusion increases, as assessed by blood-flow sensitive techniques, are as reliable as language-related hemispheric perfusion increases. METHODS: The reproducibility of hemispheric blood flow velocity increases during a line bisection task was assessed with functional transcranial Doppler sonography. RESULTS: Over repeated examinations, the index of lateralization of 20 healthy subjects showed a high test-retest reproducibility (r=0.9, P<0.01). No practice effects were detected over the course of 10 re-assessments of one subject. CONCLUSIONS: Hemispheric lateralization of visuospatial attention is a robust phenomenon and can be reliably determined using perfusion sensitive measurements. Future studies should focus on investigating lesion-related reorganization of attentional processing with blood-flow sensitive techniques.
Authors: Andreas Jansen; Agnes Flöel; Michael Deppe; Jutta van Randenborgh; Bianca Dräger; Martin Kanowski; Stefan Knecht Journal: Hum Brain Mapp Date: 2004-11 Impact factor: 5.038
Authors: Andrew J O Whitehouse; Nicholas Badcock; Margriet A Groen; Dorothy V M Bishop Journal: J Int Neuropsychol Soc Date: 2009-08-27 Impact factor: 2.892