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Literature DB >> 1204799

Quantitative morphological investigations on smooth muscle cells in vascular surgical specimens and their clinical importance.

W Feigl, H Sinzinger, O Wagner, C Leithner.

Abstract

A distinct distribution of activated SMC could be demonstrated in atherosclerotic plaques and the neighbouring media of human beings. An increased proliferation was found in the younger age group and generally in the marginal regions of the plaques. The occurrence of activated SMC is thought to be a sequel of metabolic hypoxic damages. A high frequency of activated SMC is a bad prognostic sign in surgical specimens indicating a tendency for proliferation and occlusion.

Entities: Disease Species

Mesh：

Year: 1975 PMID： 1204799 DOI： 10.1007/bf01945822

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

11 in total

1. A modified alcian blue-periodic acid Schiff stain for epoxy-embedded atherosclerotic arteries.

Authors: H F Hoff; C Rayburn
Journal: Stain Technol Date: 1974-07

2. [Electron microscopy studies on the behavior of smooth muscle cells in the arterial wall under various experimental conditions].

Authors: K P Backwinkel; H Themann; G Schmitt; W H Hauss
Journal: Virchows Arch A Pathol Pathol Anat Date: 1973-04-19

3. Reaction of the aortic wall of the rabbit after superficial, longitudinal, mechanical trauma.

Authors: S Björkerud
Journal: Virchows Arch A Pathol Pathol Anat Date: 1969

4. Experimental aortic intimal thickening. I. Morphology and source of intimal cells.

Authors: W S Webster; S P Bishop; J C Geer
Journal: Am J Pathol Date: 1974-08 Impact factor: 4.307

5. Alterations in population dynamics of arterial smooth muscle cells during atherogenesis. I. Activation of interphase cells in cholesterol-fed swine prior to gross atherosclerosis demonstrated by "postpulse-salvage labeling".

Authors: W A Thomas; R A Florentin; S C Nam; J M Reiner; K T Lee
Journal: Exp Mol Pathol Date: 1971-10 Impact factor: 3.362

6. Preproliferative phase of atherosclerosis in swine fed cholesterol.

Authors: W A Thomas; R A Florentin; S C Nam; D N Kim; R M Jones; K T Lee
Journal: Arch Pathol Date: 1968-12

7. Preliminary experience with mitotic activity of cellular elements in the atherosclerotic plaques of cholesterol-fed rabbits studied by labeling with tritiated thymidine.

Authors: G C McMillan; H C Stary
Journal: Ann N Y Acad Sci Date: 1968-11-21 Impact factor: 5.691

8. Evidence for a monoclonal origin of human atherosclerotic plaques.

Authors: E P Benditt; J M Benditt
Journal: Proc Natl Acad Sci U S A Date: 1973-06 Impact factor: 11.205

9. Atherosclerosis and the arterial smooth muscle cell: Proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosis.

Authors: R Ross; J A Glomset
Journal: Science Date: 1973-06-29 Impact factor: 47.728