Literature DB >> 12047606

Effects of Yoku-kan-san-ka-chimpi-hange on the sleep of normal healthy adult subjects.

Rika Aizawa1, Takashi Kanbayashi, Yasushi Saito, Yuriko Ogawa, Tomonari Sugiyama, Tsuyoshi Kitajima, Yoshihiko Kaneko, Masahito Abe, Tetsuo Shimizu.   

Abstract

Yoku-kan-san-ka-chimpi-hange (YKCH) is a drug used for insomnia in Japanese traditional herbal medicine. The present study evaluated the effects of YKCH on sleep by all-night polysomnography using the double-blind method. Yoku-kan-san-ka-chimpi-hange increased the total sleep time significantly, and tended to cause an increase in sleep efficiency and of stage 2 sleep, as well as a decrease of sleep latency and of stage 3 + 4 sleep. There was no apparent influence on rapid eye movement (REM) sleep. In terms of non-REM sleep, the effects of YKCH exhibit a profile similar to those of benzodiazepines.

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Year:  2002        PMID： 12047606     DOI： 10.1046/j.1440-1819.2002.01006.x

Source DB:  PubMed          Journal:  Psychiatry Clin Neurosci        ISSN： 1323-1316            Impact factor:   5.188


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