Literature DB >> 1204741

Antagonistic effects of pemoline to colchicine and caffeine.

W Röper.   

Abstract

Pemoline, the constituent of Tradon, is able to slow down the decrease of the mitotic index caused by 0.1% caffeine in roots of Vicia faba, and mitotic aberrations are reduced. With 0.005% colchicine and 3 x 10(-4) g/ml pemoline, no metaphase-accumulation can be observed, and anaphase-disorder is delayed.

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Year:  1975        PMID： 1204741     DOI： 10.1007/bf02326793

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  6 in total

1.  [5-Phenyl-2-imino-4-oxo-oxazolidine, a central stimulant substance].

Authors:  L SCHMIDT
Journal:  Arzneimittelforschung       Date:  1956-08

2.  The mitotic apparatus, a possible site of action of gibberellic acid.

Authors:  M Fragata
Journal:  Naturwissenschaften       Date:  1970-03

3.  Partial mitotic index and phase indices.

Authors:  J F López-Sáez; E Fernández-Gómez
Journal:  Experientia       Date:  1965-10-15

4.  Protective effect of magnesium pemoline against lethal doses of x-irradiation.

Authors:  H LeVan
Journal:  Experientia       Date:  1967-12-15

5.  Changes in mitotic indices in roots of Vicia faba. I. Antagonistic effect of colchicine and IAA.

Authors:  D Davidson; R D MacLeod
Journal:  Chromosoma       Date:  1966       Impact factor: 4.316

6.  The mechanism of action of colchicine. Colchicine binding to sea urchin eggs and the mitotic apparatus.

Authors:  G G Borisy; E W Taylor
Journal:  J Cell Biol       Date:  1967-08       Impact factor: 10.539
  6 in total

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