| Literature DB >> 12047365 |
A Bohnert1, M Schürmann, A Hartung, H Hackstein, J Müller-Quernheim, G Bein.
Abstract
We typed 241 members of 62 sarcoidosis families with 136 affected siblings for three single nucleotide polymorphisms of the interleukin-4 receptor alpha-chain gene (IL4R). Allele frequencies in patients were compared to those of healthy unrelated control individuals. The segregation of the three-point IL4R haplotypes completed by two flanking highly polymorphic microsatellite polymorphisms revealed no evidence for linkage of the IL4R gene locus with sarcoidosis.Entities:
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Year: 2002 PMID： 12047365 DOI： 10.1046/j.1365-2370.2002.00291.x
Source DB: PubMed Journal: Eur J Immunogenet ISSN： 0960-7420