Literature DB >> 1204721

Evidence for purine biosynthesis in human leukocytes.

R Marcolongo, G Pompucci, V Micheli.   

Abstract

Human leukocytes and lymphocytes have shown to be equipped with 5-phosphoribosyl-1-pyrophosphate amidotransrease, the enzyme which catalyzes the synthesis of the first intermediate of the purine pathway, thus providing evidence that these cells have the capacity for de novo purine biosynthesis.

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Year:  1975        PMID: 1204721     DOI: 10.1007/bf02326754

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  6 in total

1.  The regulation of activity of phosphoribosyl-pyrophosphate amidotransferase by purine ribonacleotides: a potential feedback control of purine biosyntoesis.

Authors:  J B WYNGAARDEN; D M ASHTON
Journal:  J Biol Chem       Date:  1959-06       Impact factor: 5.157

2.  Properties of 5-phosphoribosyl-1-pyrophosphate amidotransferase from human lymphoblasts.

Authors:  A W Wood; J E Seegmiller
Journal:  J Biol Chem       Date:  1973-01-10       Impact factor: 5.157

Review 3.  The biological significance of purine salvage.

Authors:  A W Murray
Journal:  Annu Rev Biochem       Date:  1971       Impact factor: 23.643

4.  Glycine-C-14 incorporation into nucleic acid purine by leucocytes obtained from normal and gouty subjects.

Authors:  H S Diamond; M Friedland; D Halberstam; D Kaplan
Journal:  Ann Rheum Dis       Date:  1969-05       Impact factor: 19.103

5.  Human leukocyte metabolism in vitro. I. Incorporation of adenine-8-C-14 and formate-C-14 into the nucleic acids of leukemic leukocytes.

Authors:  J L SCOTT
Journal:  J Clin Invest       Date:  1962-01       Impact factor: 14.808

6.  De novo purine biosynthesis by two pathways in Burkitt lymphoma cells and in human spleen.

Authors:  G H Reem
Journal:  J Clin Invest       Date:  1972-05       Impact factor: 14.808

  6 in total

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