| Literature DB >> 12045354 |
Takuji Yoshida1, Masakazu Nishiyachi, Nobuyuki Nakashima, Masayuki Murase, Eiichi Kotani.
Abstract
The Stille coupling reaction of stannylindole 12 with 4-iodoimidazole 13 (or 24) in the presence of PdCl(2)(PPh(3))(2) gave the corresponding indole-imidazole coupling product 14 (or 25), thereby affording a new synthetic approach to the alkaloid granulatimide (7), isolated from the Brazilian ascidian Didemnum granulatum, as well as its structural analogues, 10-methylgranulatimide (23), 17-methylgranulatimide (30), 10,17-dimethylgranulatimide (31).Entities:
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Year: 2002 PMID: 12045354 DOI: 10.1248/cpb.50.872
Source DB: PubMed Journal: Chem Pharm Bull (Tokyo) ISSN: 0009-2363 Impact factor: 1.645