Patrick A Ball1, Gil Hardy. 1. School of Pharmacy, Department of Clinical Pharmacy, University of Auckland, Building 504, 85 Park Road, Grafton, Auckland, New Zealand. p.ball@auckland.ac.nz
Abstract
OBJECTIVE: We reviewed the literature and examined the issues surrounding the use of glutamine in pediatrics and neonatology. METHODS: We reviewed the literature using Medline, Embase, Current Contents, and International Pharmaceutical Abstracts. Additional information was obtained from bibliographic citations and personal communications. RESULTS: Evidence showed that glutamine levels are affected in a number of life stages and conditions. Useful, indicative studies are emerging but many fail to demonstrate significant differences. The problems of researching in this patient population were demonstrated. CONCLUSION: A need for a great deal of further research in this area, including larger multicenter trials, clearly emerged.
OBJECTIVE: We reviewed the literature and examined the issues surrounding the use of glutamine in pediatrics and neonatology. METHODS: We reviewed the literature using Medline, Embase, Current Contents, and International Pharmaceutical Abstracts. Additional information was obtained from bibliographic citations and personal communications. RESULTS: Evidence showed that glutamine levels are affected in a number of life stages and conditions. Useful, indicative studies are emerging but many fail to demonstrate significant differences. The problems of researching in this patient population were demonstrated. CONCLUSION: A need for a great deal of further research in this area, including larger multicenter trials, clearly emerged.
Authors: Marcel J I J Albers; Ewout W Steyerberg; Frans W J Hazebroek; Marjan Mourik; Gerard J J M Borsboom; Trinet Rietveld; Jan G M Huijmans; Dick Tibboel Journal: Ann Surg Date: 2005-04 Impact factor: 12.969
Authors: Reinaldo B Oriá; Carlos Meton G Vieira; Relana C Pinkerton; Carlos M de Castro Costa; Maria Beatriz Lopes; Isa Hussaini; Weibin Shi; Gerly A C Brito; Aldo A M Lima; Richard L Guerrant Journal: Nutr Res Date: 2006-08 Impact factor: 3.315