Literature DB >> 12044346

DNA methyltransferases get connected to chromatin.

Wendy A Burgers, François Fuks, Tony Kouzarides.   

Abstract

The DNA methyltransferases (Dnmts) are responsible for the generation of genomic methylation patterns, which lead to transcriptional silencing. Recent studies have identified new protein partners for the Dnmts revealing novel mechanisms by which they can be targeted to specific genomic regions to silence genes. In particular, the links identified with histone deacetylases, histone methyltransferases and SNF-2-like ATPases are defining new requirements for the functioning of Dnmts. A picture is emerging whereby the Dnmts are intimately connected to the chromatin environment in which they are working.

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Year:  2002        PMID： 12044346     DOI： 10.1016/S0168-9525(02)02667-7

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.639


  43 in total

1.  Activation of the early B-cell-specific mb-1 (Ig-alpha) gene by Pax-5 is dependent on an unmethylated Ets binding site.

Authors:  Holly Maier; Jeff Colbert; Daniel Fitzsimmons; Dawn R Clark; James Hagman
Journal:  Mol Cell Biol       Date:  2003-03       Impact factor: 4.272

2.  Deacetylase activity is required for recruitment of the basal transcription machinery and transactivation by STAT5.

Authors:  Anne Rascle; James A Johnston; Bruno Amati
Journal:  Mol Cell Biol       Date:  2003-06       Impact factor: 4.272

3.  Association of Lsh, a regulator of DNA methylation, with pericentromeric heterochromatin is dependent on intact heterochromatin.

Authors:  Qingsheng Yan; Edward Cho; Stephen Lockett; Kathrin Muegge
Journal:  Mol Cell Biol       Date:  2003-12       Impact factor: 4.272

4.  Myc represses transcription through recruitment of DNA methyltransferase corepressor.

Authors:  Carmen Brenner; Rachel Deplus; Céline Didelot; Axelle Loriot; Emmanuelle Viré; Charles De Smet; Arantxa Gutierrez; Davide Danovi; David Bernard; Thierry Boon; Pier Giuseppe Pelicci; Bruno Amati; Tony Kouzarides; Yvan de Launoit; Luciano Di Croce; François Fuks
Journal:  EMBO J       Date:  2004-12-16       Impact factor: 11.598

5.  Recruitment of the de novo DNA methyltransferase Dnmt3a by Kaposi's sarcoma-associated herpesvirus LANA.

Authors:  Meir Shamay; Anita Krithivas; Jun Zhang; S Diane Hayward
Journal:  Proc Natl Acad Sci U S A       Date:  2006-09-18       Impact factor: 11.205

6.  Safeguarding parental identity: Dnmt1 maintains imprints during epigenetic reprogramming in early embryogenesis.

Authors:  Miguel R Branco; Masaaki Oda; Wolf Reik
Journal:  Genes Dev       Date:  2008-06-15       Impact factor: 11.361

7.  HDA6, a putative histone deacetylase needed to enhance DNA methylation induced by double-stranded RNA.

Authors:  Werner Aufsatz; M Florian Mette; Johannes van der Winden; Marjori Matzke; Antonius J M Matzke
Journal:  EMBO J       Date:  2002-12-16       Impact factor: 11.598

Review 8.  DNA methylation: the future of crime scene investigation?

Authors:  Branka Gršković; Dario Zrnec; Sanja Vicković; Maja Popović; Gordan Mršić
Journal:  Mol Biol Rep       Date:  2013-05-07       Impact factor: 2.316

9.  DNA-methyltransferase 1 mRNA is selectively overexpressed in telencephalic GABAergic interneurons of schizophrenia brains.

Authors:  M Veldic; H J Caruncho; W S Liu; J Davis; R Satta; D R Grayson; A Guidotti; E Costa
Journal:  Proc Natl Acad Sci U S A       Date:  2003-12-18       Impact factor: 11.205

10.  Prolonged transcriptional silencing and CpG methylation induced by siRNAs targeted to the HIV-1 promoter region.

Authors:  Kazuo Suzuki; Toshiaki Shijuuku; Toshihiko Fukamachi; John Zaunders; Gilles Guillemin; David Cooper; Anthony Kelleher
Journal:  J RNAi Gene Silencing       Date:  2005-10-11
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