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Literature DB >> 1204251

Immunoglobulin synthesis and antibody content in the small intestine of the rabbit.

Abstract

The concentration of immunoglobulin and specific antibody in the serum and the intestinal fluid and the rate of synthesis of immunoglobulin in the small intestine was measured in normal and immunized rabbits. IgA was found to be the predominant immunoglobulin in the intestinal fluid. IgA and IgG were secreted at rates of 4-3 mug/cm/hr and 1-3 mug/cm/hr respectively. Specific anti-Vibrio cholerae antibodies in the intestine were found mainly in the IgA class after oral immunization.

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Year: 1975 PMID： 1204251 PMCID： PMC1538147

Source DB: PubMed Journal: Clin Exp Immunol ISSN： 0009-9104 Impact factor: 4.330

18 in total

Review 1. The demonstration and function of antibodies in the gastrointestinal tract.

Authors: D J Shearman; D M Parkin; D B McClelland
Journal: Gut Date: 1972-06 Impact factor: 23.059

Review 2. Secretory immunoglobulins.

Authors: T B Tomasi; J Bienenstock
Journal: Adv Immunol Date: 1968 Impact factor: 3.543

3. Isolation and biological properties of three classes of rabbit antibody to Vibrio cholerae.

Authors: E J Steele; W Chaicumpa; D Rowley
Journal: J Infect Dis Date: 1974-08 Impact factor: 5.226

Review 4. Gastrointestinal structure and function in germ-free or gnotobiotic animals.

Authors: G R Thompson; P C Trexler
Journal: Gut Date: 1971-03 Impact factor: 23.059

5. Immunochemical quantitation of antigens by single radial immunodiffusion.

Authors: G Mancini; A O Carbonara; J F Heremans
Journal: Immunochemistry Date: 1965-09

6. Distribution of poliovirus antibody in serum, nasopharynx and alimentary tract following segmental immunization of lower alimentary tract with poliovaccine.

Authors: P L Ogra; D T Karzon
Journal: J Immunol Date: 1969-06 Impact factor: 5.422

7. Cholera immunology. I. Immunoglobulin levels in serum, fluid from the small intestine, and feces from patients with cholera and noncholeraic diarrhea during illness and convalescence.

Authors: R H Waldman; Z Bencić; R Sakazaki; R Sinha; R Ganguly; B C Deb; S Mukerjee
Journal: J Infect Dis Date: 1971-06 Impact factor: 5.226

8. The isolation and biologic activities of purified secretory IgA and IgG anti-Salmonella typhimurium "O" antibodies from rabbit intestinal fluid and colostrum.

Authors: D S Eddie; M L Schulkind; J B Robbins
Journal: J Immunol Date: 1971-01 Impact factor: 5.422