Literature DB >> 12042402

Neuromuscular blockers--a means of palliation?

L Hawryluck1.   

Abstract

As we die, our respiratory pattern is altered and we seem to gasp and struggle for each breath. Such gasping is commonly seen as a clear sign of dyspnoea and suffering by families and loved ones, however, it is unclear whether it is perceived at all by the dying person. Narcotics and sedatives do not seem to affect these gasping respirations. In this issue of the Journal of Medical Ethics, we are asked to consider whether the last gasp of a dying patient could be or, perhaps, even should be avoided by administering neuromuscular blockers to palliate dying patients. For many reasons, such as our current failure to alleviate pain and distress, stories of inadequate analgesia and sedation in critically ill paralysed patients and the inability to know the intent-whether to palliate or to euthanise-it would seem that administering neuromuscular blockers should not be ethically permissible.

Entities:  

Keywords:  Death and Euthanasia

Mesh:

Substances:

Year:  2002        PMID: 12042402      PMCID: PMC1733578          DOI: 10.1136/jme.28.3.170

Source DB:  PubMed          Journal:  J Med Ethics        ISSN: 0306-6800            Impact factor:   2.903


  7 in total

1.  Pharmacologic paralysis and withdrawal of mechanical ventilation at the end of life.

Authors:  R D Truog; J P Burns; C Mitchell; J Johnson; W Robinson
Journal:  N Engl J Med       Date:  2000-02-17       Impact factor: 91.245

Review 2.  The rule of double effect: clearing up the double talk.

Authors:  D P Sulmasy; E D Pellegrino
Journal:  Arch Intern Med       Date:  1999-03-22

3.  Ethical debate: The distinction between withdrawing life sustaining treatment under the influence of paralysing agents and euthanasia. Are we treading a fine line?

Authors:  K Street; J Henderson
Journal:  BMJ       Date:  2001-08-18

4.  Who is entitled to double effect?

Authors:  J Boyle
Journal:  J Med Philos       Date:  1991-10

5.  The rule of double effect--a critique of its role in end-of-life decision making.

Authors:  T E Quill; R Dresser; D W Brock
Journal:  N Engl J Med       Date:  1997-12-11       Impact factor: 91.245

6.  The Supreme Court speaks--not assisted suicide but a constitutional right to palliative care.

Authors:  R A Burt
Journal:  N Engl J Med       Date:  1997-10-23       Impact factor: 91.245

7.  The agony of agonal respiration: is the last gasp necessary?

Authors:  R M Perkin; D B Resnik
Journal:  J Med Ethics       Date:  2002-06       Impact factor: 2.903

  7 in total
  3 in total

1.  Dutch pediatricians' views on the use of neuromuscular blockers for dying neonates: a qualitative study.

Authors:  K ten Cate; S van de Vathorst
Journal:  J Perinatol       Date:  2015-01-22       Impact factor: 2.521

2.  Internists' attitudes towards terminal sedation in end of life care.

Authors:  L C Kaldjian; J F Jekel; J L Bernene; G E Rosenthal; M Vaughan-Sarrazin; T P Duffy
Journal:  J Med Ethics       Date:  2004-10       Impact factor: 2.903

Review 3.  Ethical reflections on end-of-life signs and symptoms in the intensive care setting: a place for neuromuscular blockers?

Authors:  Cédric Daubin; Lise Haddad; Dominique Folscheid; Alexandre Boyer; Ludivine Chalumeau-Lemoine; Olivier Guisset; Philippe Hubert; Jérôme Pillot; René Robert; Didier Dreyfuss
Journal:  Ann Intensive Care       Date:  2014-07-08       Impact factor: 6.925

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.