Literature DB >> 1203915

Effects of local anaesthetics on calcium transport by canine cardiac microsomes (fragmented sarcoplasmic reticulum).

A M Katz, D I Repke, S Corkedale, J Schwarz.   

Abstract

Local anaesthetics inhibit calcium transport by cardiac sarcoplasmic reticulum. However, the concentrations of lidocaine and procaineamide needed to produce these effects are high. No significant differences were found between these agents that could account for reported differences in their electrophysiological effects.

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Year:  1975        PMID: 1203915     DOI: 10.1093/cvr/9.6.764

Source DB:  PubMed          Journal:  Cardiovasc Res        ISSN: 0008-6363            Impact factor:   10.787


  2 in total

1.  Effects of tetracaine and procaine on skinned muscle fibres depend on free calcium.

Authors:  G K Pike; J J Abramson; G Salama
Journal:  J Muscle Res Cell Motil       Date:  1989-10       Impact factor: 2.698

2.  Anesthetics alter the physical and functional properties of the Ca-ATPase in cardiac sarcoplasmic reticulum.

Authors:  B S Karon; L M Geddis; H Kutchai; D D Thomas
Journal:  Biophys J       Date:  1995-03       Impact factor: 4.033

  2 in total

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