Literature DB >> 12039003

Metal ions and prion diseases.

Sylvain Lehmann1.   

Abstract

Recent data demonstrate that transition metal ions such as copper not only bind the prion protein with high affinities, but also modify its biochemical properties. This has important consequences for the potential function of the protein in metal-ion transport or as an anti-oxidant molecule. In addition, this relationship between the prion protein and metal ions is likely to play a critical role in the physiopathology of prion diseases.

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Year:  2002        PMID： 12039003     DOI： 10.1016/s1367-5931(02)00295-8

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN： 1367-5931            Impact factor:   8.822


  22 in total

Review 1.  Bioinorganic chemistry in the postgenomic era.

Authors:  Ivano Bertini; Antonio Rosato
Journal:  Proc Natl Acad Sci U S A       Date:  2003-03-24       Impact factor: 11.205

2.  A new method to determine the structure of the metal environment in metalloproteins: investigation of the prion protein octapeptide repeat Cu(2+) complex.

Authors:  Matthias Mentler; Andreas Weiss; Klaus Grantner; Pablo del Pino; Dominga Deluca; Stella Fiori; Christian Renner; Wolfram Meyer Klaucke; Luis Moroder; Uwe Bertsch; Hans A Kretzschmar; Paul Tavan; Fritz G Parak
Journal:  Eur Biophys J       Date:  2004-09-28       Impact factor: 1.733

3.  Anion effects on sodium ion and acid molecule adduction to protein ions in electrospray ionization mass spectrometry.

Authors:  Tawnya G Flick; Samuel I Merenbloom; Evan R Williams
Journal:  J Am Soc Mass Spectrom       Date:  2011-08-09       Impact factor: 3.109

Review 4.  The crucial role of metal ions in neurodegeneration: the basis for a promising therapeutic strategy.

Authors:  Alessandra Gaeta; Robert C Hider
Journal:  Br J Pharmacol       Date:  2005-12       Impact factor: 8.739

5.  Probing the role of PrP repeats in conformational conversion and amyloid assembly of chimeric yeast prions.

Authors:  Jijun Dong; Jesse D Bloom; Vladimir Goncharov; Madhuri Chattopadhyay; Glenn L Millhauser; David G Lynn; Thomas Scheibel; Susan Lindquist
Journal:  J Biol Chem       Date:  2007-09-24       Impact factor: 5.157

Review 6.  Redox control of prion and disease pathogenesis.

Authors:  Neena Singh; Ajay Singh; Dola Das; Maradumane L Mohan
Journal:  Antioxid Redox Signal       Date:  2010-06-01       Impact factor: 8.401

7.  Gold nanorods 3D-supercrystals as surface enhanced Raman scattering spectroscopy substrates for the rapid detection of scrambled prions.

Authors:  Ramón A Alvarez-Puebla; Ashish Agarwal; Pramit Manna; Bishnu P Khanal; Paula Aldeanueva-Potel; Enrique Carbó-Argibay; Nicolas Pazos-Pérez; Leonid Vigderman; Eugene R Zubarev; Nicholas A Kotov; Luis M Liz-Marzán
Journal:  Proc Natl Acad Sci U S A       Date:  2011-05-02       Impact factor: 11.205

8.  Experimental and computational studies of the macrocyclic effect of an auxiliary ligand on electron and proton transfers within ternary copper(II)-histidine complexes.

Authors:  Tao Song; Corey N W Lam; Dominic C M Ng; Galina Orlova; Julia Laskin; De-Cai Fang; Ivan K Chu
Journal:  J Am Soc Mass Spectrom       Date:  2009-01-23       Impact factor: 3.109

9.  Ligand binding promotes prion protein aggregation--role of the octapeptide repeats.

Authors:  Shuiliang Yu; Shaoman Yin; Nancy Pham; Poki Wong; Shin-Chung Kang; Robert B Petersen; Chaoyang Li; Man-Sun Sy
Journal:  FEBS J       Date:  2008-11       Impact factor: 5.542

10.  Perturbation of T-cell development by insertional mutation of a PrP transgene.

Authors:  Mark Zabel; Christina Greenwood; Alana M Thackray; Bruce Pulford; Willem Rens; Raymond Bujdoso
Journal:  Immunology       Date:  2008-10-21       Impact factor: 7.397
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