Literature DB >> 12038909

The hidden research paper.

Richard Horton1.   

Abstract

CONTEXT: To determine whether the views expressed in a research paper are accurate representations of contributors' opinions about the research being reported.
METHODS: Purposive sampling of 10 research articles published in The Lancet; qualitative analysis of answers to 6 questions about the meaning of the study put to contributors who were listed on the byline of these articles. Fifty-four contributors listed on the bylines of the 10 articles were evaluated, and answers to questions were compared between contributors within research groups and against the published research report.
RESULTS: A total of 36 (67%) of 54 contributors replied to this survey. Important weaknesses were often admitted on direct questioning but were not included in the published article. Contributors frequently disagreed about the importance of their findings, implications, and directions for future research. I could find no effort to study systematically past evidence relating to the investigators' own findings in either survey responses or the published article. Overall, the diversity of contributor opinion was commonly excluded from the published report. I found that discussion sections were haphazardly organized and did not deal systematically with important questions about the study.
CONCLUSIONS: A research paper rarely represents the opinions of those scientists whose work it reports. The findings described herein reveal evidence of (self-)censored criticism, obscured meanings, confused assessment of implications, and failures to indicate directions for future research. There is now empirical support for the introduction of structured discussion sections in research papers. Editors might also explore ways to recover the plurality of contributors' opinions.

Keywords:  Biomedical and Behavioral Research; Empirical Approach

Mesh:

Year:  2002        PMID: 12038909     DOI: 10.1001/jama.287.21.2775

Source DB:  PubMed          Journal:  JAMA        ISSN: 0098-7484            Impact factor:   56.272


  11 in total

1.  Bias in the research literature and conflict of interest: an issue for publishers, editors, reviewers and authors, and it is not just about the money.

Authors:  Simon N Young
Journal:  J Psychiatry Neurosci       Date:  2009-11       Impact factor: 6.186

2.  Paranormal beliefs and cognitive function: A systematic review and assessment of study quality across four decades of research.

Authors:  Charlotte E Dean; Shazia Akhtar; Tim M Gale; Karen Irvine; Dominique Grohmann; Keith R Laws
Journal:  PLoS One       Date:  2022-05-04       Impact factor: 3.752

3.  Misrepresentation of randomized controlled trials in press releases and news coverage: a cohort study.

Authors:  Amélie Yavchitz; Isabelle Boutron; Aida Bafeta; Ibrahim Marroun; Pierre Charles; Jean Mantz; Philippe Ravaud
Journal:  PLoS Med       Date:  2012-09-11       Impact factor: 11.069

4.  Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.

Authors:  A Cecile J W Janssens; John P A Ioannidis; Sara Bedrosian; Paolo Boffetta; Siobhan M Dolan; Nicole Dowling; Isabel Fortier; Andrew N Freedman; Jeremy M Grimshaw; Jeffrey Gulcher; Marta Gwinn; Mark A Hlatky; Holly Janes; Peter Kraft; Stephanie Melillo; Christopher J O'Donnell; Michael J Pencina; David Ransohoff; Sheri D Schully; Daniela Seminara; Deborah M Winn; Caroline F Wright; Cornelia M van Duijn; Julian Little; Muin J Khoury
Journal:  Eur J Epidemiol       Date:  2011-04       Impact factor: 8.082

5.  Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.

Authors:  A Cecile J W Janssens; John P A Ioannidis; Sara Bedrosian; Paolo Boffetta; Siobhan M Dolan; Nicole Dowling; Isabel Fortier; Andrew N Freedman; Jeremy M Grimshaw; Jeffrey Gulcher; Marta Gwinn; Mark A Hlatky; Holly Janes; Peter Kraft; Stephanie Melillo; Christopher J O'Donnell; Michael J Pencina; David Ransohoff; Sheri D Schully; Daniela Seminara; Deborah M Winn; Caroline F Wright; Cornelia M van Duijn; Julian Little; Muin J Khoury
Journal:  Eur J Hum Genet       Date:  2011-05       Impact factor: 4.246

Review 6.  The reproducibility of biomedical research: Sleepers awake!

Authors:  Stephen A Bustin
Journal:  Biomol Detect Quantif       Date:  2015-01-21

7.  Occurrence and nature of questionable research practices in the reporting of messages and conclusions in international scientific Health Services Research publications: a structured assessment of publications authored by researchers in the Netherlands.

Authors:  Reinie G Gerrits; Tessa Jansen; Joko Mulyanto; Michael J van den Berg; Niek S Klazinga; Dionne S Kringos
Journal:  BMJ Open       Date:  2019-05-15       Impact factor: 2.692

8.  Peer review in open access scientific journals.

Authors:  Matthew E Falagas
Journal:  Open Med       Date:  2007-04-14

Review 9.  Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and elaboration.

Authors:  Jan P Vandenbroucke; Erik von Elm; Douglas G Altman; Peter C Gøtzsche; Cynthia D Mulrow; Stuart J Pocock; Charles Poole; James J Schlesselman; Matthias Egger
Journal:  PLoS Med       Date:  2007-10-16       Impact factor: 11.069

10.  All that glitters isn't gold: a survey on acknowledgment of limitations in biomedical studies.

Authors:  Gerben Ter Riet; Paula Chesley; Alan G Gross; Lara Siebeling; Patrick Muggensturm; Nadine Heller; Martin Umbehr; Daniela Vollenweider; Tsung Yu; Elie A Akl; Lizzy Brewster; Olaf M Dekkers; Ingrid Mühlhauser; Bernd Richter; Sonal Singh; Steven Goodman; Milo A Puhan
Journal:  PLoS One       Date:  2013-11-20       Impact factor: 3.240

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