| Literature DB >> 12036189 |
Abstract
Interstitial cells of Cajal (ICC) in the guinea pig intestine, identified by the tyrosine kinase receptor, c-Kit, have been shown with immunohistochemistry to express nucleotide P2X2 and P2X5 receptors. P2X5 receptors have also been demonstrated on interstitial cells in the mouse ileum. It is speculated that release of ATP from enteric nerves, enteric glial cells or from contracting smooth muscle may provide a feedback mechanism for pacemaker activity in the intestine.Entities:
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Year: 2002 PMID: 12036189 DOI: 10.1016/s1566-0702(02)00005-x
Source DB: PubMed Journal: Auton Neurosci ISSN: 1566-0702 Impact factor: 3.145