Literature DB >> 12036074

5-Bromo-2'-deoxyuridine efficiently suppresses division potential of the yeast Saccharomyces cerevisiae.

Michihiko Fujii1, Hisasi Ito, Tsutomu Hasegawa, Toshikazu Suzuki, Noritaka Adachi, Dai Ayusawa.   

Abstract

We established a thymidine-auxotrophic strain of the yeast Saccharomyces cerevisiae to examine biological effects of thymidine analogues. 5-Bromo-2'-deoxyuridine efficiently suppressed the division potential of yeast showing morphology similar to senescent cells.

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Year:  2002        PMID： 12036074     DOI： 10.1271/bbb.66.906

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  5 in total

1.  Bromodeoxyuridine induces senescence in neural stem and progenitor cells.

Authors:  Heather H Ross; Lindsay H Levkoff; Gregory P Marshall; Maria Caldeira; Dennis A Steindler; Brent A Reynolds; Eric D Laywell
Journal:  Stem Cells       Date:  2008-09-18       Impact factor: 6.277

2.  Identification of genes that affect sensitivity to 5-bromodeoxyuridine in the yeast Saccharomyces cerevisiae.

Authors:  Michihiko Fujii; Kensuke Miki; Shinichi Takayama; Dai Ayusawa
Journal:  Mol Genet Genomics       Date:  2010-03-30       Impact factor: 3.291

3.  Overexpression of HAM1 gene detoxifies 5-bromodeoxyuridine in the yeast Saccharomyces cerevisiae.

Authors:  Shinichi Takayama; Michihiko Fujii; Aya Kurosawa; Noritaka Adachi; Dai Ayusawa
Journal:  Curr Genet       Date:  2007-09-27       Impact factor: 3.886

4.  Bromodeoxyuridine inhibits cancer cell proliferation in vitro and in vivo.

Authors:  Lindsay H Levkoff; Gregory P Marshall; Heather H Ross; Maria Caldeira; Brent A Reynolds; Meryem Cakiroglu; Christopher L Mariani; Wolfgang J Streit; Eric D Laywell
Journal:  Neoplasia       Date:  2008-08       Impact factor: 5.715

5.  Regulation of transcription termination by glucosylated hydroxymethyluracil, base J, in Leishmania major and Trypanosoma brucei.

Authors:  David Reynolds; Laura Cliffe; Konrad U Förstner; Chung-Chau Hon; T Nicolai Siegel; Robert Sabatini
Journal:  Nucleic Acids Res       Date:  2014-08-07       Impact factor: 16.971
  5 in total

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