| Literature DB >> 12034026 |
William L Ragland1, Renata Novak, John El-Attrache, Vladimir Savić, Katja Ester.
Abstract
Chicken anemia virus (CAV) and infectious bursal disease virus (IBDV) are the two most important viruses that cause immunosuppression in commercial chickens. Because inapparent, subclinical infections by these viruses cause immunosuppression, there is need for assessment of the immune status of chickens. Interference with induction of transcription for chicken interferon-alpha (ChIFN-alpha) and ChIFN-gamma was noted after subclinical infections with either CAV or IBDV. Because the immunosuppressive viruses of chickens may interfere with transcription for ChIFN-alpha and ChIFN-gamma, we propose using this interference to assess the immune status of chickens.Entities:
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Year: 2002 PMID: 12034026 DOI: 10.1089/10799900252952226
Source DB: PubMed Journal: J Interferon Cytokine Res ISSN: 1079-9907 Impact factor: 2.607