| Literature DB >> 12033255 |
Vladimir I Baranov1, Zoë Quinn, Dmitry R Bandura, Scott D Tanner.
Abstract
We report a set of novel immunoassays in which proteins of interest can be detected using specific element-tagged antibodies. These immunoassays are directly coupled with an inductively coupled plasma mass spectrometer (ICPMS) to quantify the elemental (in this work, metal) component of the reacted tagged antibodies. It is demonstrated that these methods can detect levels of target proteins as low as 0.1-0.5 ng/mL and yield a linear response to protein concentration over 3 orders of magnitude.Mesh：
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Year: 2002 PMID： 12033255 DOI： 10.1021/ac0110350
Source DB: PubMed Journal: Anal Chem ISSN： 0003-2700 Impact factor: 6.986