| Literature DB >> 12031320 |
Françoise M Perron-Sierra1, Alain Pierré, Mike Burbridge, Nicolas Guilbaud.
Abstract
Novel bicyclic tetrahydropyrano[3,2-d]oxazolones derivatives, analogues of Fumagillin, were synthesised via a stereocontrolled oxidative-rearrangement of furylcarbinols and subsequent treatment with the appropriate isocyanate. These compounds demonstrated potent antiangiogenic activity.Entities:
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Year: 2002 PMID： 12031320 DOI： 10.1016/s0960-894x(02)00197-x
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823