Literature DB >> 12031276

Stem cells in the treatment of Parkinson's disease.

E Arenas1.   

Abstract

Stem cells have been suggested as candidate therapeutic tools for neurodegenerative disorders, given their ability to give rise to the appropriate cell types after grafting in vivo. In this review I summarize some of the evidence currently available concerning two approaches for the treatment of Parkinson's disease: (1) The generation of dopaminergic neurons from embryonic stem cells, multipotent stem cells, and neuronal progenitor cells for cell replacement therapy. (2) The engineering of multipotent stem cells to release glial cell-line derived neurotrophic factor, a potent neurotrophic factor for dopaminergic neurons, in a neuroprotective and neuroregenerative approach to the treatment of Parkinson's disease.

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Year:  2002        PMID： 12031276     DOI： 10.1016/s0361-9230(01)00772-9

Source DB:  PubMed          Journal:  Brain Res Bull        ISSN： 0361-9230            Impact factor:   4.077


  19 in total

1.  Effects of Sertoli cell-conditioned medium on ventral midbrain neural stem cells: a preliminary report.

Authors:  Rania Shamekh; Samuel Saporta; Don F Cameron; Alison E Willing; Cindy D Sanberg; Karl Johe; P R Sanberg
Journal:  Neurotox Res       Date:  2008 May-Jun       Impact factor: 3.911

2.  Creatine Enhances Transdifferentiation of Bone Marrow Stromal Cell-Derived Neural Stem Cell Into GABAergic Neuron-Like Cells Characterized With Differential Gene Expression.

Authors:  Shahram Darabi; Taki Tiraihi; AliReza Delshad; Majid Sadeghizadeh; Taher Taheri; Hayder K Hassoun
Journal:  Mol Neurobiol       Date:  2016-02-24       Impact factor: 5.590

3.  A novel function of dcf1 during the differentiation of neural stem cells in vitro.

Authors:  Lei Wang; Jiao Wang; Yiliu Wu; Jie Wu; Shuya Pang; Rong Pan; Tieqiao Wen
Journal:  Cell Mol Neurobiol       Date:  2008-03-26       Impact factor: 5.046

Review 4.  Genetic engineered molecular imaging probes for applications in cell therapy: emphasis on MRI approach.

Authors:  In K Cho; Silun Wang; Hui Mao; Anthony Ws Chan
Journal:  Am J Nucl Med Mol Imaging       Date:  2016-09-22

Review 5.  Embryonic and adult stem cells as a source for cell therapy in Parkinson's disease.

Authors:  Yossef S Levy; Merav Stroomza; Eldad Melamed; Daniel Offen
Journal:  J Mol Neurosci       Date:  2004       Impact factor: 3.444

6.  Surgical management of Parkinson's disease: update and review.

Authors:  Y Chao; L Gang; Z L Na; W Y Ming; W S Zhong; W S Mian
Journal:  Interv Neuroradiol       Date:  2008-02-01       Impact factor: 1.610

7.  Changes in the content of estrogen alpha and progesterone receptors during differentiation of mouse embryonic stem cells to dopamine neurons.

Authors:  Néstor F Díaz; Christian Guerra-Arraiza; Néstor E Díaz-Martínez; Patricia Salazar; Anayansi Molina-Hernández; Ignacio Camacho-Arroyo; Ivan Velasco
Journal:  Brain Res Bull       Date:  2007-02-28       Impact factor: 4.077

8.  BMP and TGF-β pathway mediators are critical upstream regulators of Wnt signaling during midbrain dopamine differentiation in human pluripotent stem cells.

Authors:  Jingli Cai; Stephanie Schleidt; Joshua Pelta-Heller; Danielle Hutchings; Gregory Cannarsa; Lorraine Iacovitti
Journal:  Dev Biol       Date:  2013-01-23       Impact factor: 3.582

9.  Detection of calcium transients in embryonic stem cells and their differentiated progeny.

Authors:  Jason S Meyer; Gregory Tullis; Christopher Pierret; Kathleen M Spears; Jason A Morrison; Mark D Kirk
Journal:  Cell Mol Neurobiol       Date:  2009-12       Impact factor: 5.046

10.  Cellular immune response to intrastriatally implanted allogeneic bone marrow stromal cells in a rat model of Parkinson's disease.

Authors:  Dianne M Camp; David A Loeffler; Diane M Farrah; Jade N Borneman; Peter A LeWitt
Journal:  J Neuroinflammation       Date:  2009-06-05       Impact factor: 8.322
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