Literature DB >> 12031090

Collagenous fibroma (desmoplastic fibroblastoma) of the finger in a child.

Jun Nishio1, Hiroshi Iwasaki, Takeo Nishijima, Masahiro Kikuchi.   

Abstract

Collagenous fibroma (desmoplastic fibroblastoma) is a distinctive benign fibrous soft tissue tumor that typically occurs in the subcutaneous tissue or skeletal muscle in adults. We describe a case of collagenous fibroma in a 7-year-old boy who presented with a 1-cm solitary, firm nodule on the volar aspect of the metacarpophalangeal joint of the left little finger. Microscopically, the tumor was composed of spindle- and stellate-shaped cells embedded in a hypovascular, densely collagenous stroma. No mitotic figures, calcifications or necrosis were identified. Immunohistochemically, tumor cells were diffusely positive for vimentin, but negative for smooth muscle actin, muscle-specific actin, desmin, cytokeratin, S-100 protein or CD34. To our knowledge, this is the second reported case of collagenous fibroma in children. Our case report indicates that the clinicopathological features of collagenous fibroma in childhood are similar to those in adults.

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Year:  2002        PMID: 12031090     DOI: 10.1046/j.1440-1827.2002.01351.x

Source DB:  PubMed          Journal:  Pathol Int        ISSN: 1320-5463            Impact factor:   2.534


  5 in total

Review 1.  An Update on Clinicopathological, Imaging and Genetic Features of Desmoplastic Fibroblastoma (Collagenous Fibroma).

Authors:  Shizuhide Nakayama; Jun Nishio; Mikiko Aoki; Kazuki Nabeshima; Takuaki Yamamoto
Journal:  In Vivo       Date:  2021 Jan-Feb       Impact factor: 2.155

2.  Desmoplastic fibroblastoma of the finger tip in an adult.

Authors:  Ji Hwan Kim; Deuk Young Oh; Sang Wha Kim; Jung Ho Lee; Sang Tae Ahn; Jong Won Rhie
Journal:  Arch Plast Surg       Date:  2012-01-15

3.  Updates on the cytogenetics and molecular cytogenetics of benign and intermediate soft tissue tumors.

Authors:  Jun Nishio
Journal:  Oncol Lett       Date:  2012-10-30       Impact factor: 2.967

4.  [Desmoplastic fibroma on arm of 22-year-old woman].

Authors:  D Helbig; J C Simon; T Wetzig; U Paasch
Journal:  Hautarzt       Date:  2010-10       Impact factor: 0.751

5.  Collagenous fibroma (desmoplastic fibroblastoma) of the neck presenting with neurological symptoms.

Authors:  Farina Fong; Edward Odell; Ricard Simo
Journal:  Head Neck Pathol       Date:  2008-12-10
  5 in total

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