Literature DB >> 12031010

Maternal thyrotoxicosis causing central hypothyroidism in infants.

Y S Lee1, K Y Loke, S C Y Ng, R Joseph.   

Abstract

We describe three infants born to mothers with poorly controlled Graves' disease, who developed transient central hypothyroidism in the immediate postnatal period. Suppression of the fetal pituitary-thyroid axis may be due to placental transfer of thyroxine from the hyperthyroid mother. This may persist for months postnatally, necessitating treatment to optimise neurodevelopmental outcome.

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Year:  2002        PMID: 12031010     DOI: 10.1046/j.1440-1754.2002.00741.x

Source DB:  PubMed          Journal:  J Paediatr Child Health        ISSN: 1034-4810            Impact factor:   1.954


  2 in total

Review 1.  Hyperthyroidism and pregnancy.

Authors:  Helen Marx; Pina Amin; John H Lazarus
Journal:  BMJ       Date:  2008-03-22

2.  Central congenital hypothyroidism caused by maternal thyrotoxicosis.

Authors:  Daphne Peeters; Sandra van Gijlswijk; Ralph W Leunissen; Danielle C M van der Kaay
Journal:  BMJ Case Rep       Date:  2018-03-22
  2 in total

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